To evaluate the accuracy of pupil fields and determine the normative pupillary response data by age using a newly developed head-mounted perimeter.
A total of 100 healthy subjects (20–68▒y of age) were enrolled. The newly developed head-mounted perimeter “imo” was used to measure the percentage pupil constriction (PPC) as response to a stimulus at all 36 test points of the visual field. Goldmann size III and V stimuli at 0, 8, and 11 decibels (dB) under 31.4, 6, and 3 apostilbs (asb) background were presented. The PPC correlations of the right and left eyes (r) were examined. Reproducibility was determined with the coefficient of variation (CV) and a Bland-Altman plot. Mean PPC were analyzed as normative data in all 36 test points.
Excellent correlation between both eyes was obtained for Goldmann size V stimuli, target luminance of 0▒dB, and a background luminance of 31.4 asb (r=0.83, P<0.001). From the test-retest CV peripheral areas have low reproducibility compared with central areas. With a Goldmann size V target, there was a steeper decline of the PPC from the center to the periphery field, and the temporal field PPC was larger than the nasal. No major differences were observed between the PPC data and the age groups by decade (e.g., center 3°, P=0.223–0.913).
Normative PPC data might well be useful for assessing objective visual fields with the newly developed head-mounted perimeter.
*Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan
†Kagurazaka Minamino Eye Clinic, Tokyo, Japan
‡Department of Ophthalmology, Kitasato University, School of Medicine, Kanagawa, Japan
Acknowledgements: This study was supported by a grant from Kitasato University School of Allied Health Sciences Grant in-Aid for Research Project, grant number 2017-1039 and by JSPS KAKENHI grant number JP16K21346.
Funding: This study was funded by CREWT Medical Systems. The funders provided the device (free borrowing at 2▒y).
Disclosures: Ken Asakawa, funded by CREWT Medical Systems; Mami Nanno, None; Hitoshi Ishikawa, None; Nobuyuki Shoji, None.
Disclosure: The authors declare no conflict of interest.
Reprints: Ken Asakawa, PhD, Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, 1-15-1 Kitasato, Sagamihara, Minami-ku, Kanagawa 252-0373, Japan (e-mail: email@example.com).
Received March 8, 2018
Accepted June 18, 2018