Glaucoma Telemedicine and Screening: Original StudiesAlabama Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (AL-SIGHT): Study Design and MethodologyRhodes, Lindsay A. MD, MSPH*; Register, Shilpa OD, PhD*; Asif, Irfan MD†; McGwin, Gerald Jr MS, PhD*,‡; Saaddine, Jinan MD, MPH§; Nghiem, Van Thi Ha PhD∥; Owsley, Cynthia PhD, MSPH*; Girkin, Christopher A. MD, MSPH* Author Information Departments of *Ophthalmology and Visual Sciences †Family and Community Medicine, School of Medicine Departments of ‡Epidemiology ∥Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, Birmingham, AL §Vision Health Initiative, Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA Trial Registration Number: NCT04328207. This research was supported by a cooperative agreement with the Centers for Disease Control and Prevention (1U01DP006441) and National Eye Institute grants (NIH/NEI 1K23EY025724-01A1 and P30EY03039), with supplemental support from the EyeSight Foundation of Alabama, Birmingham, AL, and Research to Prevent Blindness, New York, NY. Disclosure: The authors declare no conflict of interest. Reprints: Lindsay A. Rhodes, MD, MSPH, Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, 1720 University Blvd, Suite 601, Birmingham, AL 35233 (e-mail: [email protected]). Journal of Glaucoma: May 2021 - Volume 30 - Issue 5 - p 371-379 doi: 10.1097/IJG.0000000000001794 Buy Metrics Abstract Précis: This paper presents the methods and protocol of a community-based telemedicine program to identify glaucoma and other eye diseases. Purpose: To describe the study rationale and design of the Alabama Screening and Intervention for Glaucoma and eye Health through Telemedicine project. Methods: The study will implement and evaluate a telemedicine-based detection strategy for glaucoma, diabetic retinopathy, and other eye diseases in at-risk patients seen at federally qualified health centers located in rural Alabama. The study will compare the effectiveness of the remote use of structural and functional ocular imaging devices to an in-person examination. Study participants will receive a remote ocular assessment consisting of visual acuity, intraocular pressure, visual field testing, and imaging of the retina and optic nerve with spectral-domain optical coherence tomography, and the data will be reviewed by an ophthalmologist and optometrist. It will also compare the effectiveness of financial incentives along with a validated patient education program versus a validated patient education program alone in improving follow-up adherence. Finally, cost and cost-effectiveness analyses will be performed on the telemedicine program compared with standard in-person care using effectiveness measured in numbers of detected eye disease cases. Conclusions: The study aims to develop a model eye health system using telemedicine to prevent vision loss and address eye health among underserved and at-risk populations. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.