Online Articles: Case Report/Small Case SeriesLong-term Follow-up of 14 Eyes With Bilateral and Multiple Ciliary Body Cysts: Prognosis of this Rare EntityHugo, Juliette MD*,†; Feumi, Charles MD*,‡; Morin, Adèle MD*; Nguyen, Michelle MD*; Lachkar, Yves MD*Author Information *Marie-Therese Health Center, Saint-Joseph Hospital ‡Ophtalmopôle, Cochin Hospital, Paris †APHM, Ophthalmology Department, Nord Hospital, Marseille, France Disclosure: The authors declare no conflict of interest. Reprints: Juliette Hugo, MD, North Hospital, Marseille 13015, France (e-mail: [email protected]). Journal of Glaucoma: January 2021 - Volume 30 - Issue 1 - p e13-e17 doi: 10.1097/IJG.0000000000001693 Buy SDC Metrics Abstract Purpose: To describe the long-term outcomes of eyes with bilateral and multiple ciliary body cysts (CBC). Methods: This retrospective study included patients with multiple and bilateral CBC diagnosed by high-resolution ultrasound biomicroscopy and followed by a single glaucoma specialist from 2000 to 2020. All patients underwent complete ophthalmic examination including dynamic indentation gonioscopy, retinal nerve fiber layer (RNFL) measurement by optic coherence tomography and automated perimetry. Results: Seven patients (14 eyes) with bilateral and multiple CBC were included with a mean follow-up of 98±39 months. Four eyes of 2 patients had complete angle closure at first examination and 3 of them underwent trabeculectomy with good visual outcomes. Four eyes of 2 patients had a reversible angle-closure at first examination and underwent a ultrasound biomicroscopy–guided laser peripheral iridotomy (LPI) which reopened the irido-corneal angles. Two of these eyes needed intensification of hypotensive drops during the follow-up. Among the 6 eyes (3 patients) with open angle at first examination, all had had LPI at last follow-up visit, 5 had normal RNFL and visual field and 1 received an additional hypotensive drop because of RNFL progression. Conclusion: Our long-term cohort of bilateral and multiple CBC demonstrates that this rare entity may have a good prognosis if LPI is performed before extension of peripheral anterior synechiae. Irreversible angle closure required trabeculectomy in 75% of cases in our cohort with however good visual outcomes. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.