Online Articles: Case Report/Small Case SeriesJuvenile Open-angle Glaucoma With Waardenburg Syndrome: A Case ReportAbdelRahman, Ahmed M. MD, FRCSEd; Amin, Rana H. MD, FRCS(gl)Author Information Kasr Al-Aini Hospital, Cairo University, Cairo, Egypt Disclosure: The authors declare no conflict of interest. Reprints: Rana H. Amin, MD, FRCS(gl), Royal Valley Compound, Safwa City Region, Sheikh Zayed, Giza 12588, Egypt (e-mail: [email protected]). Journal of Glaucoma: January 2021 - Volume 30 - Issue 1 - p e1-e4 doi: 10.1097/IJG.0000000000001676 Buy Metrics Abstract Waardenburg syndrome (WS) is a genetic disorder resulting in anomalies of derivatives of neural crest cells during development. Patients tend to have variable degrees of pigmentary defects affecting skin, hair, and irides in addition to hearing loss and possible systemic neurological associations. Elevation of the intraocular pressure has been reported in several adult patients with WS. We report the first case of WS to be associated with juvenile open-angle glaucoma in a 20-year-old Egyptian man thus expanding the spectrum of the types of glaucoma that can coexist with the syndrome. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.