PerspectiveIs Diabetes Mellitus a Blessing in Disguise for Primary Open-angle Glaucoma?Hou, Huiyuan MD, PhD*; Moghimi, Sasan MD*; Baxter, Sally L. MD, MSc*,†; Weinreb, Robert N. MD*Author Information *Viterbi Family Department of Ophthalmology, Hamilton Glaucoma Center, Shiley Eye Institute †Department of Medicine, Division of Biomedical Informatics, University of California San Diego, La Jolla, CA Disclosure: R.N.W.: Research support—Carl Zeiss Meditec, Centervue, Heidelberg Engineering, Konan, National Eye Institute, Optovue; Consultant—Allergan, Bausch & Lomb, Eyenovia. Novartis, Nicox. The remaining authors declare no conflict of interest. Reprints: Robert N. Weinreb, MD, Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, CA 92037 (e-mail: [email protected]). Journal of Glaucoma: January 2021 - Volume 30 - Issue 1 - p 1-4 doi: 10.1097/IJG.0000000000001719 Buy Metrics Abstract Although numbers of studies have addressed this question, the relationship between diabetes mellitus and primary open-angle glaucoma is still unclear. This article discusses progress in understanding the complex relationship between these 2 entities and recent shifts in perspective that challenge the traditional dogma regarding diabetes mellitus and primary open-angle glaucoma. There are still many unanswered questions. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.