Case Report/Small Case SeriesCase Series of Stickler Syndrome Presenting With Acute Angle ClosureWalters, Alexander MD; Lambert, Nathan MD; Bricel, Seth MD; Hwang, Thomas MD; Ing, Eliesa MD; Tehrani, Shandiz MD, PhDAuthor Information Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR This work was supported by grant P30EY010572 from the National Institutes of Health (Bethesda, MD) and by an unrestricted grant from Research to Prevent Blindness (New York, NY). Both patients underwent informed consent before laser and incisional surgeries. This report does not contain any personal information that could lead to the identification of the patients. Disclosure: The authors declare no conflict of interest. Reprints: Shandiz Tehrani, MD, PhD, Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, 515 SW Campus Dr., Portland, OR 97239 (e-mail: email@example.com). Journal of Glaucoma: October 2020 - Volume 29 - Issue 10 - p 992-994 doi: 10.1097/IJG.0000000000001591 Buy Metrics Abstract Purpose: Stickler syndrome is associated with open-angle glaucoma, but no reports exist of adults presenting with acute angle closure. Here, we report the clinical associations and short-term outcomes in 2 patients with Stickler syndrome who presented with acute angle closure at a single tertiary referral center. Observations: A 36-year-old female with Stickler syndrome presented with acute onset of red and painful left eye with cloudy vision. Initial intraocular pressure (IOP) was measured to be 54 mm Hg. Gonioscopy revealed no angle structures or peripheral anterior synechiae in the left eye. Two laser peripheral iridotomies were created 5 days apart without adequate IOP lowering. Left eye cataract extraction with intraocular lens implantation and Ahmed glaucoma drainage device implantation were performed with resolution of ocular hypertension. A 35-year-old male with Stickler syndrome presented with intermittent right eye pain and blurry vision. IOP was 42 mm Hg and gonioscopy revealed 270 degrees of angle closure in the right eye. The patient underwent laser peripheral iridotomy in the right eye with resolution of ocular hypertension by the next day. Conclusions: Recognizing angle closure as a potential feature of Stickler syndrome can help providers adequately screen and manage patients with Stickler syndrome presenting with acutely elevated IOP. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.