Review ArticlesAnterior Segment Optical Coherence Tomography Is There a Clinical Role in the Management of Primary Angle Closure Disease?Nongpiur, Monisha E. MD, PhD*,†; Tun, Tin A. MD*; Aung, Tin FRCS(Ed), PhD*,†,‡Author Information *Singapore Eye Research Institute, Singapore National Eye Centre †Duke-NUS Medical School ‡Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Supported by National Medical Research Council, Singapore (NMRC/STAR/0023/2014). Disclosure: The authors declare no conflict of interest. Reprints: Monisha E. Nongpiur, MD, PhD, Singapore Eye Research Institute, The Academia, 20 College Road, Discovery Tower Level 6, Singapore 169856, Singapore (e-mail: email@example.com). Received May 27, 2019 Accepted August 12, 2019 Online date: September 5, 2019 Journal of Glaucoma: January 2020 - Volume 29 - Issue 1 - p 60–66 doi: 10.1097/IJG.0000000000001355 Buy Metrics Abstract Primary angle closure disease (PACD) covers a spectrum that includes primary angle closure suspect, primary angle closure, primary angle closure glaucoma, and acute primary angle closure. Accumulating evidence suggests that the pathogenesis of PACD is complex, with multiple contributory factors including variations in the anatomic or biometric characteristics of the angle segment structures. Advances in anterior segment optical coherence tomography technology have further enhanced our understanding of the risk factors and mechanisms involved in the disease process. This review discusses the potential clinical role of the anterior segment optical coherence tomography in the diagnosis, mechanistic evaluation, and as a predictor for future clinical outcomes of patients with PACD. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.