To report a peculiar case of adult-onset buphthalmos.
Review of the medical record of a 24-year-old patient with Down syndrome who developed buphthalmos in the left eye after corneal transplantation for keratoconus.
In the next 2 years after surgery, the operated eye evolved with chronic anterior uveitis that led to progressive peripheral synechiae, oscillating intraocular pressure, cataract, graft failure, and buphthalmos.
The finding of buphthalmos of adult-onset in Down syndrome raises important issues concerning the classification of this eye condition and the responsibility for detecting and monitoring eyes with glaucoma in individuals with chromosome 21 trisomy.
Department of Ophthalmology, School of Medicine of Ribeirão Preto, University of São Paulo, Avenida Bandeirantes, Ribeirão Preto, São Paulo, Brazil
No source of support for this work, including sources of the National Institutes of Health (NIH); Wellcome Trust; Howard HughesMedical Institute (HHMI); and other(s).
Disclosure: The authors declare no conflict of interest.
Reprints: Sidney J. Faria-e-Sousa, MD, PhD, Department of Ophthalmology, School of Medicine of Ribeirão Preto, University of São Paulo, Avenida Bandeirantes, 3900, Ribeirão Preto 14049-900, São Paulo, Brazil (e-mail: email@example.com).
Received September 10, 2018
Accepted October 14, 2018