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Newborn Glaucoma: Do not Forget Infections

Kaushik, Sushmita, MS*; Kataria, Pankaj, MS*; Joshi, Gunjan, MS*; Singh, Mini P., MS; Ram, Jagat, MS*

doi: 10.1097/IJG.0000000000000992
Online Articles: Case Report/Small Case Series

Intrauterine infections can affect various structures of the developing fetal eye. Rubella infection results in congenital cataracts, keratopathy, retinopathy and less commonly, glaucoma. Ophthalmic manifestations of intrauterine cytomegalovirus (CMV) infection have been reported to be chorioretinitis, optic nerve colobomas, and corneal opacities, but have not been implicated in congenital cataract or congenital glaucoma. Concurrent infection with both rubella and CMV virus has not been reported. We report concurrent rubella and CMV infection in a baby born with corneal opacification, severe congenital glaucoma, and congenital cataract. It is important to recognize these babies early and investigate for intrauterine infections rather than assume they are all primary congenital glaucoma. Involvement of the cornea, glaucoma, and cataract make management of these babies a major challenge requiring a multidisciplinary team approach.

*Postgraduate Institute of Medical Education and Research

Department of Virology, Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Disclosure: The authors declare no conflict of interest.

Reprints: Sushmita Kaushik, MS, Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India (e-mail:

Received April 8, 2018

Accepted April 27, 2018

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