Microphthalmia, Dermal Aplasia, and Sclerocornea Syndrome: Endoscopic Cyclophotocoagulation in the Management of Congenital GlaucomaThompson, Atalie, C., MD, MPH*; Thompson, Matthew, O., MD†; Lim, Maria, E., MD*; Freedman, Sharon, F., MD*; Enyedi, Laura, B., MD*Journal of Glaucoma: January 2018 - Volume 27 - Issue 1 - p e7–e10 doi: 10.1097/IJG.0000000000000812 Online Articles: Case Report/Small Case Series Abstract Author Information Purpose: To report on the use of endoscopic cyclophotocoagulation (ECP) to treat congenital glaucoma in a triple X female with microphthalmia, dermal aplasia, and sclerocornea (MIDAS) syndrome. Observations: The patient demonstrated linear streaks on the face and neck consistent with dermal aplasia. The corneas were scleralized with ectatic areas of corneal thinning, and the eyes were microphthalmic. Ultrasound biomicroscopy demonstrated congenital aphakia and iris stumps. The patient had elevated intraocular pressure (IOP) that responded to topical glaucoma therapy in the right but not the left eye. Intraoperative endoscopy of the posterior segment revealed multiple hypopigmented chorioretinal lacunae surrounding a pale, cupped optic nerve. ECP of the ciliary processes in the left eye led to marked improvement in IOP. Conclusions and Importance: Patients with MIDAS syndrome can develop congenital glaucoma secondary to angle dysgenesis. This is the first case report to demonstrate the safe and effective use of ECP to treat elevated IOP in a patient with MIDAS. Departments of *Ophthalmology †Radiology, Duke University, Durham, NC Disclosure: The authors declare no conflict of interest. Reprints: Atalie C. Thompson, MD, MPH, 2351 Erwin Road, Hudson Room 4527, Durham, NC 27705 (e-mails: email@example.com; firstname.lastname@example.org). Received October 7, 2017 Accepted October 9, 2017 Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.