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Association of Intraocular Pressure Changes With Right Ventricular Diameter and Brain Natriuretic Peptide in a Case of Pulmonary Arterial Hypertension

Sato, Chiaki MD; Kaneko, Hiroki MD, PhD; Kondo, Takahisa MD, PhD; Takayama, Kei MD; Yasuda, Shunsuke MD, PhD; Terasaki, Hiroko MD, PhD

doi: 10.1097/IJG.0000000000000371
Online Articles: Case Reports

Purpose: To report a case of secondary pulmonary arterial hypertension (PAH) and the relationship of intraocular pressure (IOP) change with right ventricular diameter (RVD) and brain natriuretic peptide (BNP).

Methods: Case report.

Patient: A 22-year-old woman with dilated and congested conjunctival and episcleral veins was diagnosed with high IOP. She was previously diagnosed with Sjögren syndrome and suffered from secondary PAH.

Results: The RVD and BNP level improved and the IOP decreased with routine treatment for PAH. During self-cessation of treatment for PAH, the RVD, BNP level, and IOP deteriorated. However, they improved after treatment was reinitiated.

Conclusion: There was a synchronizing change in the parameters representing high pulmonary arterial pressure and IOP during treatment of PAH.

Departments of *Ophthalmology

Advanced Medicine in Cardiopulmonary Disease, Nagoya University Graduate School of Medicine, Nagoya, Japan

Disclosure: The authors declare no conflict of interest.

Reprints: Hiroki Kaneko, MD, PhD, Department of Ophthalmology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan (e-mail:

Received April 2, 2015

Accepted December 14, 2015

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