Functional Pituitary Tumors Masquerading as Primary Glaucoma and Effect of Hypophysectomy on Intraocular TensionGupta, Shikha MD; Sihota, Ramanjit MD; Gupta, Viney MD; Dada, Tanuj MD; Gogia, Varun MD; Sharma, Ajay BScJournal of Glaucoma: March 2015 - Volume 24 - Issue 3 - p e7–e13 doi: 10.1097/IJG.0b013e31829521f2 Online Articles: Case Reports Abstract Author InformationAuthors Article MetricsMetrics We report 2 bilateral cases that presented as primary ocular hypertension and primary angle-closure glaucoma, respectively; however, they were subsequently discovered to be harboring secretory pituitary tumors. After transsphenoidal tumor resection, intraocular pressures (IOPs) in all 4 eyes returned to normal levels. Sudden rise in IOP then again served as a primary manifestation of relapse in the second patient with growth hormone secreting pituitary tumor. It was not found feasible for resurgery; thus, patient needed trabeculectomy in both eyes to achieve an optimum control of intraocular tension. We conclude that pituitary adenomas may mimic primary glaucoma without producing vertical hemianopia and cause a reversible rise in IOP. Furthermore, a careful ongoing expert ophthalmologic assessment may serve as a useful clinical marker for early relapse in these tumors. Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India Disclosure: The authors declare no conflict of interest. Reprints: Shikha Gupta, MD, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India (e-mail: email@example.com). Received September 21, 2012 Accepted March 4, 2013 Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.