To elucidate the relationship between macular retinal thickness
and corresponding superior or inferior visual hemifield
defects in glaucoma
Thirty-nine eyes of 39 patients with open-angle glaucoma
showed superior or inferior hemifield
defects (superior hemifield
defects, 27 eyes; inferior hemifield
defects, 12 eyes). We measured the retinal thickness of the parafovea and fovea centralis corresponding to a defect or an apparently normal hemifield
by spectral domain optical coherence tomography
. We then analyzed the relationship between the retinal thickness corresponding to an apparently normal hemifield
and the severity of the glaucomatous visual field defect
on the other side of the same eye.
We found that the retinal thickness of the parafovea and fovea centralis significantly decreased, as the hemifield
defect increased. The retinal thickness of the parafovea, the inner sector, outer sector, and inner and outer sectors, corresponding to the apparently normal hemifields significantly decreased with the progression of the hemifield
defect on the other side. The mean±SD age of patients was 66.5±9.1 years and the refraction was −1.3±2.4 D.
Conclusions: Macular retinal thickness
decreases with a corresponding visual hemifield
defect in glaucoma
patients. Retinal structural changes precede the loss of the visual field in the apparently normal side.