Original StudiesEndoscopic Goniotomy Early Clinical Experience in Congenital GlaucomaKulkarni, Sadhana V. MD*; Damji, Karim F. MD, FRCSC, MBA†; Fournier, Annick V. MD, FRCSC* ‡; Pan, Irene MSc*; Hodge, William G. MD, FRCSC, PhD§ Author Information §Ivey Eye Institute, University of Western Ontario, London *Eye Institute, University of Ottawa, Ottawa Hospital Research Institute ‡Children's Hospital of Eastern Ontario, Ottawa †Department of Ophthalmology, University of Alberta, Edmonton, Canada Reprints: Sadhana Kulkarni, MD, University of Ottawa Eye Institute and Ottawa Health Research Institute, 501 Smyth Road, Ottawa, ON-K1H 8L6 (e-mail: [email protected]). Received for publication November 28, 2008 accepted June 7, 2009 Journal of Glaucoma: April 2010 - Volume 19 - Issue 4 - p 264-269 doi: 10.1097/IJG.0b013e3181b21ede Buy Metrics Abstract Purpose: To review the technique and early outcomes of endoscopic goniotomy (EG) in children with opaque corneas and primary congenital glaucoma (PCG) or developmental glaucoma with ocular or systemic anomalies (DG). Methods: EG was performed for approximately 300 degrees of the angle through temporal and superonasal corneal incisions. We retrospectively reviewed consecutive cases from 2003 to 2007. Primary outcome was intraocular pressure (IOP) change from baseline to last postoperative visit. Success was defined as IOP ≤21 mm Hg with or without medication but no further surgical intervention. Results: Fourteen eyes of 8 patients (4 PCG, 4 DG) were included. Mean age at surgery was 3.88±3.72 months. The reduction in IOP from baseline to the last follow-up visit was −16.7±16.7 mm Hg. Success was achieved in 6 of the 16 eyes (Total=43%, PCG=50%, DG=30%). Corneal diameter and axial length remained stable in all eyes. Two patients with DG needed additional surgery after 8 to 9 months. Complications included cataract and zonular dialysis both in 2 patients with aniridia. Conclusions: This pilot study indicates that EG shows reasonable potential for IOP control in congenital glaucoma. The safety and efficacy of EG needs to be further studied with a larger sample size and comparison to other angle surgery techniques. © 2010 Lippincott Williams & Wilkins, Inc.