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Trabeculectomy in Patients With Primary Angle-closure Glaucoma

Chen, Yi-Hao MD; Lu, Da-Wen MD, PhD; Cheng, Jen-Hao MD; Chen, Jiann-Torng MD, PhD; Chen, Ching-Long MD

doi: 10.1097/IJG.0b013e31819c4a07
Original Studies

Purpose To analyze the results of trabeculectomy in patients with primary angle-closure glaucoma.

Methods A retrospective and noncomparative case series analysis was performed on data from Taiwan, from 2001 to 2004. The outcomes of trabeculectomy in eyes with acute primary angle-closure glaucoma attack (AACG) and those with chronic primary angle-closure glaucoma (CACG) were assessed in terms of final intraocular pressure (IOP), changes to visual acuity, and the incidence of complications.

Results A total of 52 eyes of 52 patients, 15 patients in AACG group and 37 patients in CACG group, were reviewed. The mean follow-up period was 32 months (range, 26-42 mo). In terms of no visual acuity change after surgery, there were significant differences between the CACG and AACG groups (P=0.02, Fisher exact test). In terms of final IOP control, trabeculectomy outcome was significantly worse in patients in the AACG group than those in the CACG group (P<0.01, Fisher exact test). Moreover, the complication of bleb encapsulation appeared more frequently in the AACG group than in the CACG group (P=0.02, Fisher exact test).

Conclusions Compared with CACG, trabeculectomy may not be as good for patients of AACG, because it may lead to worsened visual acuity; it also seems to present a greater failure rate, more complications, and fewer cases of surgical survival.

Department of Ophthalmology, Tri-Service General Hospital, Taipei, Taiwan

Reprints: Da-Wen Lu, MD, PhD, Department of Ophthalmology, Tri-Service General Hospital, No. 325, Sec. 2, Cheng-Kong Rd., Taipei, Taiwan, 114 (e-mail:

Received for publication August 27, 2008; accepted January 4, 2009

© 2009 Lippincott Williams & Wilkins, Inc.