Autoimmunity and GlaucomaGrus, Franz H. MD, PhD; Joachim, Stephanie C. MD; Wuenschig, Diana Dipl. Biol.; Rieck, Jochen Dipl. Biol.; Pfeiffer, Norbert MDJournal of Glaucoma: January-February 2008 - Volume 17 - Issue 1 - p 79-84 doi: 10.1097/IJG.0b013e318156a592 Special Article Buy Abstract Author InformationAuthors Article MetricsMetrics Elevated intraocular pressure does not explain glaucoma in all patients, but there is information that autoimmune mechanisms may be involved in this disorder. This review attempts to reveal the findings about specific changes in autoantibody profiles in glaucoma patients and their possible role in glaucoma. Considering that these changes in natural autoimmunity can be found consistently among different study populations, it might be a promising new tool for glaucoma detection. Experimental Ophthalmology, Department of Ophthalmology, Johannes Gutenberg University, Mainz, Germany Reprints: Franz H. Grus, MD, PhD, Experimental Ophthalmology, Department of Ophthalmology, Johannes Gutenberg University, Langenbeckstrasse 1, 55101 Mainz, Germany (e-mail: email@example.com). Received for publication February 12, 2007; accepted July 10, 2007 © 2008 Lippincott Williams & Wilkins, Inc.