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Gastritis staging as a clinical priority

Mescoli, Claudiaa; Gallo Lopez, Alyc; Taxa Rojas, Luisd; Jove Oblitas, Walkere; Fassan, Matteoa; Rugge, Massimoa,b

European Journal of Gastroenterology & Hepatology: February 2018 - Volume 30 - Issue 2 - p 125–129
doi: 10.1097/MEG.0000000000001015
Review Articles

The elective background for gastric adenocarcinoma is the atrophic transformation of the gastric mucosa. The extent of mucosal atrophy basically parallels the risk of developing gastric cancer. This means that either noninvasive (serology) or invasive (endoscopy/histology) methods enabling the atrophic transformation to be quantified can be used theoretically to assess a given patient’s gastric cancer risk. This review aims to focus on the reliability of histology gastritis Operative Link for Gastritis Assessment -staging system for assessing the ‘personalized’ cancer risk in individuals with (atrophic) gastritis.

aSurgical Pathology and Cytopathology Unit, Department of Medicine (DIMED), University of Padova

bVeneto Tumor Registry (RTV), Veneto Regional Authority, Padova, Italy

cProyecta Diagnostico Scientific Research Center-CONCYTEC Instituto de Investigación de la Facultad de Medicina Humana de la Universidad de San Martín de Porres

dDepartment of Pathology, Instituto Nacional de Enfermedades Neoplásicas INEN, Lima

eGastroenterology Division, Honorio Delgado Hospital, Arequipa, Peru

Correspondence to Massimo Rugge, Surgical Pathology and Cytopathology Unit, Department of Medicine (DIMED), University of Padova, Via A. Gabelli, 61, 35121 Padova, Italy Tel: +39 049 821 8990; fax: +39 049 827 2277; e-mail:

Received August 26, 2017

Accepted September 5, 2017

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