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Abdominal pain in adults with cystic fibrosis

Nash, Edward F.a; Ohri, Chandra M.b; Stephenson, Anne L.c; Durie, Peter R.d

European Journal of Gastroenterology & Hepatology: February 2014 - Volume 26 - Issue 2 - p 129–136
doi: 10.1097/MEG.0000000000000011
Review Articles

Abdominal pain is a common symptom in individuals with cystic fibrosis (CF). As prognosis has improved, CF has changed from a pediatric disease to the current situation wherein most people with CF are adults. With improved survival, the spectrum of pathologies causing abdominal pain in CF has shifted. Despite this, there have been relatively few previous publications focusing on gastrointestinal disease in CF adults. The aim of this review was to examine the characteristics, differential diagnosis, investigation, and optimal management of adults with CF presenting with abdominal pain.

aWest Midlands Adult Cystic Fibrosis Centre, Heart of England NHS Foundation Trust, Birmingham

bLeicester Adult Cystic Fibrosis Centre, Glenfield Hospital, Leicester, UK

cToronto Adult CF Clinic, St Michael’s Hospital

dDepartment of Pediatrics, The Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

All supplementary digital content is available directly from the corresponding author.

Correspondence to Edward F. Nash, MRCP(UK), West Midlands Adult Cystic Fibrosis Centre, Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham, B9 5SS, UK Tel: +44 121 424 1669; fax: +44 121 424 1661; e-mail:

Received June 9, 2013

Accepted September 17, 2013

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins