Cerebral revascularization in acute stroke requires robust diagnostic tools close to symptom onset. The quantitative National Institute of Health Stroke Scale (NIHSS) is widely used in-hospital, whereas shorter and less specific stroke scales are used in the prehospital field. This study explored the accuracy and potential clinical benefit of using NIHSS prehospitally.
Thirteen anesthesiologists trained in prehospital critical care enrolled patients with suspected acute stroke in a mobile stroke unit. NIHSS was completed twice in the acute phase: first prehospitally and then by an on-call resident neurologist at the receiving hospital. The agreement between prehospital and in-hospital NIHSS scores was assessed by a Bland–Altman plot, and inter-rater agreement for predefined clinical categories was tested using Cohen’s κ.
This Norwegian Acute Stroke Prehospital Project study included 40 patients for analyses. The mean numerical difference between prehospital and in-hospital NIHSS scores was 0.85, with corresponding limits of agreement from −5.94 to 7.64. Inter-rater agreement (κ) for the corresponding clinical categories was 0.38. A prehospital diagnostic workup (NIHSS and computed tomographic examination) was completed in median (quartiles) 10 min (range: 7–14 min). Time between the prehospital and in-hospital NIHSS scores was median (quartiles) 40 min (32–48 min).
Critical care physicians in a mobile stroke unit may use the NIHSS as a clinical tool in the assessment of patients experiencing acute stroke. The disagreement in NIHSS scores was mainly for very low values and would not have changed the handling of the patients.
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aDepartment of Research and Development, The Norwegian Air Ambulance Foundation, Drøbak
bDepartment of Health Studies, University of Stavanger
cThe Regional Centre for Emergency Medical Research and Development, Stavanger
dDepartment of Global Public Health and Primary Care, University of Bergen
eNational Centre for Emergency Primary Health Care, Uni Research Health, Bergen
fDepartment of Neurology, Østfold Hospital, Kalnes
gDepartment of Clinical Medicine, University of Oslo
hDepartment of Neurology, Oslo University Hospital, Oslo, Norway
Correspondence to Maren R. Hov, MD, Department of Research and Development, The Norwegian Air Ambulance Foundation, Holterveien 24, 1448 Drøbak, Norway Tel: +47 934 58492; fax: +47 649 04445; e-mail: firstname.lastname@example.org
Received July 27, 2017
Accepted November 19, 2017