Review Article: Gynaecological CancerAlcohol and gynecological cancers: an overviewHjartåker, Anettea; Meo, Margrethe S.a; Weiderpass, Elisabetea b c dAuthor Information aDepartment of Etiological Research, Cancer Registry of Norway, Oslo bInstitute of Community Medicine, University of Tromsø, Tromsø, Norway cDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden dDepartment of Genetic Epidemiology, Folkhälsan, Helsinki, Finland Correspondence to Dr Anette Hjartåker, PhD, Department of Etiological Research, Cancer Registry of Norway, PO Box 5313 Majorstuen, Oslo 0304, Norway Tel: +47 23 33 39 34; fax: +47 22 45 13 70; e-mail: [email protected] This study was carried out with support from Cancer Registry of Norway. Received 14 July 2009 Accepted 21 September 2009 European Journal of Cancer Prevention: January 2010 - Volume 19 - Issue 1 - p 1-10 doi: 10.1097/CEJ.0b013e328333fb3a Buy Metrics Abstract The objective of the paper was to summarize the literature findings on alcohol consumption with regard to risk of various gynecological cancers. A Medline search was performed considering available cohort and case–control studies published until 31st March 2009 examining the association between the consumption of alcoholic beverages and cancers of the cervix uteri, corpus uteri, endometrium, ovaries, vagina, and vulva. The number of prospective population-based studies with adequate information on confounding factors is low, particularly for cancers of the cervix, corpus uteri, vulva and vagina. Several register studies have found a higher risk of cervical, vulvar, and vaginal cancers among alcoholics than in the general population. However, these findings have not been confirmed in population-based studies in which confounding factors have been adjusted for. Endometrial, corpus uteri, and ovarian cancers do not seem to be related to alcohol consumption. Analyses regarding the dose–response relationship, source of alcohol (wine, beer, spirits) and interaction with other risk factors have not revealed any further associations. In conclusion, the current body of evidence, which is inadequate for several sites, suggests no association between alcohol consumption and risk of gynecological cancers. © 2010 Lippincott Williams & Wilkins, Inc.