Breast CancerProgress in breast cancer surgical managementMagnoni, Francescaa; Corso, Giovannia,b Author Information aDivision of Breast Surgery, IEO European Institute of Oncology, IRCCS bDepartment of Oncology and Hemato-Oncology, University of Milan, Via Giuseppe Ripamonti, 435, Milan, 20141 Italy Received 17 November 2021 Accepted 26 November 2021 Correspondence to Francesca Magnoni, MD, PhD, Division of Breast Surgery, European Institute of Oncology, IRCCS, Milan, Italy, Tel: +39 0294371092; e-mail: [email protected] European Journal of Cancer Prevention: November 2022 - Volume 31 - Issue 6 - p 551-553 doi: 10.1097/CEJ.0000000000000741 Buy Metrics Abstract Evolution in breast cancer surgery has been significant over these four decades. Many scientific changes have been reached, impacting daily clinical practise, thanks to scientific research and surgeons’ efforts, always tended to warrant oncological radicality as well improve women quality of life and cosmesis. Achievements in imaging, in breast cancer molecular signature characterization and patients’ genomic profile are progressively refining a sophisticated personalization of breast cancer prevention and treatment. Progress in surgery involves both primary breast site surgery and surgical axillary staging, revealing a strong propensity for a limited surgical approach and technical precision. Multimodal management and individualization are the axioms on which current research on breast cancer prevention and treatment is progressing. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.