Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Metformin for lung cancer prevention and improved survival

a novel approach

Roos, Juliana F.a; Qudsi, Mariama; Samara, Arwaa; Rahim, Madina M.a; Al-Bayedh, Samar A.a; Ahmed, Hafezb

European Journal of Cancer Prevention: July 2019 - Volume 28 - Issue 4 - p 311–315
doi: 10.1097/CEJ.0000000000000442
Review Article: Lung Cancer

Diabetes mellitus has been associated with increased risk for the development of many types of cancer. Metformin, an oral medication and first-line treatment for type 2 diabetes mellitus, has been suggested to reduce cancer risk and mortality in various types of cancer. This study focuses on assessing metformin association with lung cancer as reported in the literature. Recent studies and reviews investigating metformin effects on lung cancer incidence and patient survival are critically and systematically discussed.

aDepartment of Clinical Pharmacy and Pharmacy Practice, Dubai Pharmacy College

bDepartment of Biochemistry, Dubai Medical College, Dubai, United Arab Emirates

Correspondence to Juliana F. Roos, PhD, DipClinPharm, DipMgt, BPharm, Department of Clinical Pharmacy and Pharmacy Practice, Dubai Pharmacy College, PO Box 19099, Al Muhaisanah 1, Al Mizhar, Dubai, United Arab Emirates Tel: +971 4212 0319; fax: +971 4264 6740; e-mail:

Received November 22, 2017

Accepted January 22, 2018

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.