Supplement ArticlesTrends in net survival from head and neck cancer in six European Latin countries: results from the SUDCAN population-based studyGuizard, Anne-Valériea,b; Uhry, Zoéc,d,e,f,g; de Raucourt, Dominiqueh; Mazzoleni, Guidoi; Sánchez, Maria-Joséj,k; Ligier, Karinel; the GRELL EUROCARE-5 Working Group Author Information aGeneral Tumor Registry of Calvados bNormandie University, UNICAEN, INSERM, U1086 cDepartment of Biostatistics, University Hospital of Lyon dDepartment of Non-Communicable Diseases and Injuries, French Institute for Public Health Surveillance (Invs), Saint-Maurice eUniversity of Lyon, Lyon fUniversity of Lyon 1 gCNRS, UMR5558, Biometry and Evolutionary Biologylaboratory (LBBE), BioMaths-Health Department, Villeurbanne hDepartment of Head and Neck Surgery, François Baclesse Cancer Center, Caen iTumor Registry of South-Tyrol (Sanitary Agency for Health South-Tyrol), South-Tyrol jAndalusian School of PublicHealth, Bio-Health Research Institute (ibs.GRANADA), Granada University Hospitals/Granada University, Granada kBiomedical Research CentreNetwork for Epidemiolology and Public Health (CIBERESP), Madrid, Spain lGeneral Cancer Registry of Lille and its area, Lille, France *List of the members available at https://links.lww.com/EJCP/A137 Correspondence to Anne-Valerie Guizard, MD, Centre F. Baclesse, Avenue du General Harris BP 5026, 14076 Caen Cedex 05, France Tel: +33 02 31 45 52 45; fax: +33 02 31 45 86 32; e-mail: [email protected] European Journal of Cancer Prevention: January 2017 - Volume 26 - Issue - p S16-S23 doi: 10.1097/CEJ.0000000000000296 Buy SDC Metrics Abstract The aim of the SUDCAN collaborative study was to compare the trends in 1- and 5-year net survival and the trends in the dynamics of the excess mortality rates in head and neck cancers between six European Latin countries (Belgium, France, Italy, Portugal, Spain and Switzerland). The data were extracted from the EUROCARE-5 database. First, the net survival was studied over the 2000–2004 period using the Pohar-Perme estimator. For trend analyses, the study period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain and Switzerland and from 2000 to 2004 in Belgium and Portugal. The analyses were carried out using a flexible excess rate modelling. There were significant differences between countries in 5-year age-standardized net survivals over the 2000–2004 period, ranging from 33 to 34% in France and Portugal from 42 to 44% in Switzerland and Italy, respectively. The age-standardized net survival improved considerably from 1992 to 2004 in Italy, Spain and Switzerland, but not in France because of lack of improvement in the elderly. The increase in net survival was linked to a decrease in the excess mortality rate up to 3–4 years after diagnosis. The net survival from head and neck cancers improved over the study period, but significant differences were still observed in 2004. Differences in sex ratio and anatomical distribution contributed only partially towards these disparities. Differences in stage at diagnosis, time to treatment and/or proportion of human papillomavirus-related cases are also probably involved in the survival disparities observed. Overall, the prognosis of these tumours remains poor. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.