Research papers: Lifestyle: NutritionPizza consumption and the risk of breast, ovarian and prostate cancerGallus, Silvanoa; Talamini, Renatob; Bosetti, Cristinaa; Negri, Evaa; Montella, Maurizioc; Franceschi, Silviad; Giacosa, Attilioe; La Vecchia, Carloa fAuthor Information aIstituto di Ricerche Farmacologiche “Mario Negri”, 20157 Milan, Italy bServizio di Epidemiologia e Biostatistica, Centro di Riferimento Oncologico, 33081 Aviano (PN), Italy cIstituto Tumori “Fondazione Pascale,” Cappella dei Cangiani, 80100 Naples, Italy dInfection and Cancer Epidemiology Group, International Agency for Research on Cancer, F-69372 Lyon, cédex 08, France eGastroenterology and Nutrient Unit, National Institute for Cancer Research, 16100 Genoa, Italy fIstituto di Statistica Medica e Biometria, Università degli Studi di Milano, 20133 Milan, Italy Correspondence to: Silvano Gallus, Istituto di Ricerche Farmacologiche “Mario Negri”, Via Eritrea 62, 20157 Milan, Italy Tel: +39 02 39014 526; fax: +39 02 33200231; e-mail: [email protected] Received 10 December 2004 Accepted 9 January 2005 European Journal of Cancer Prevention: February 2006 - Volume 15 - Issue 1 - p 74-76 doi: 10.1097/01.cej.0000186632.04625.f6 Buy Metrics Abstract Pizza has been favourably related to the risk of prostate cancer in North America. Scanty information, however, is available on sex hormone-related cancer sites. We therefore studied the role of pizza consumption on the risk of breast, ovarian and prostate cancers using data from three hospital-based case–control studies conducted in Italy between 1991 and 2002. These included 2569 women with breast cancer, 1031 with ovarian cancer, 1294 men with prostate cancer, and a total of 4864 controls. Compared with non-pizza eaters, the multivariate odds ratios for eaters were 0.97 (95% confidence interval (CI) 0.86–1.10) for breast, 1.06 (95% CI 0.89–1.26) for ovarian and 1.04 (95% CI 0.88–1.23) for prostate cancer. Corresponding estimates for regular eaters (i.e. ≥1 portion per week) were 0.92 (95% CI 0.78–1.08), 1.00 (95% CI 0.80–1.25) and 1.12 (95% CI 0.88–1.43), respectively. Our results do not show a relevant role of pizza on the risk of sex hormone-related cancers. The difference with selected studies from North America suggests that dietary and lifestyle correlates of pizza eating vary between different populations and social groups. © 2006 Lippincott Williams & Wilkins, Inc.