From the aDivision of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women’s Hospital, Boston, MA
bDepartment of Medicine, Harvard Medical School, Boston, MA
cOM1, Inc., Boston, MA
dDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA
eDivision of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA
fDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
Submitted June 21, 2022; accepted March 12, 2023
K.Y., R.J.D., R.J.G., D.H.S., and S.C.K. did substantial contributions to study conception and design, acquisition of data, and analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version of the article to be published. J.L. did substantial contributions to acquisition of data; analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version of the article to be published.
Supported by R01 AR073314 (PI: S.C.K.). K.Y. received support from the Brigham and Women’s Hospital Department of Medicine Fellowship Award and NIAMS K23 AR076453 and R03 AR081309. D.H.S. receives funding from NIAMS P30AR072577.
K.Y. has received consulting fees from OM1, Inc. for unrelated work and is an employee of OM1, Inc. R.J.D. has received research support to the Brigham and Women’s Hospital from Novartis, Vertex, and Bayer for unrelated studies. R.J.G. has received funding from grants to the Brigham and Women’s Hospital from AstraZeneca, Kowa, Novartis Pharmaceuticals Corporation, and Pfizer. D.H.S. has received research support from Abbvie, Amgen, Corrona, Genentech, and Moderna for unrelated work. As well, he receives royalties from UpToDate on unrelated work. S.C.K. has received research grants to the Brigham and Women’s Hospital from Pfizer, Roche, AbbVie and Bristol-Myers Squibb for unrelated work. The other author has no conflicts to report.
Data Code Availability: The study data cannot be shared due to IRB restrictions. The authors will consider study code sharing upon a reasonable request.
Supplemental digital content is available through direct URL citations in the HTML and PDF versions of this article (www.epidem.com).
Correspondence: Kazuki Yoshida, MD, MPH, ScD, OM1, Inc., 31 St. James Ave Suite 1125, Boston MA, 02116. E-mail: [email protected].