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Air Pollution and Hospital Admissions for Cardiovascular Disease in Taipei, Taiwan

Chang, C*; Tsai, S; Yang, C

doi: 10.1097/

*Department of Environmental and Occupational Health, National Cheng Kung University, Taiwan; †Department of Healthcare Administration, I-Shou University, Taiwan; and ‡Institute of Public Health, Kaohsiung Medical University, Taiwan.


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This study was undertaken to determine whether there is an association between air pollutants levels and hospital admissions for cardiovascular diseases (CVD) in Taipei, Taiwan.

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Material and Methods:

Hospital admissions for CVD and ambient air pollution data for Taipei were obtained for the period of 1997 to 2001. The relative risk of hospital admission was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends.

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For the 1-pollutant models, on warm days (X20 1C) statistically significant positive associations were found between levels of particulate matter o10-mm aerodynamic diameter (PM10), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3). On cool days (o20 1C), all pollutants except O3 and SO2 were significantly associated with CVD admissions. For the 2-pollutant models, CO, NO2, and O3 were significant in combination with each of the other 4 pollutants on warm days. On cool days, PM10 remained statistically significant in all the 2-pollutant models.

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This study provides evidence that higher levels of ambient pollutants increase the risk of hospital admissions for CVD.

© 2007 Lippincott Williams & Wilkins, Inc.