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Commentary

“Randomize, Then Consent” or “Consent, Then Randomize”?

Revitalizing the Issue of Preconsent Randomization

Løberg, Magnus; Kalager, Mette; Bretthauer, Michael

doi: 10.1097/EDE.0000000000000469
Randomized Trial Design
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From the aDepartment of Health Management and Health Economics, University of Oslo, Oslo, Norway; bDepartment of Transplantation Medicine and KG Jebsen Center for Colorectal Cancer Research, Oslo University Hospital, Oslo, Norway; and cDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.

This paper is dedicated to our friend and mentor Marvin Zelen (1927–2014).

The authors report no conflicts of interest.

Correspondence: Michael Bretthauer, Department of Health Management and Health Economics, University of Oslo, Oslo, Norway. E-mail: michael.bretthauer@medisin.uio.no.

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