BRIEF REPORTS: PDF OnlyThe Joint Impact of Family History of Myocardial Infarction and Other Risk Factors on 12-year Coronary Heart Disease MortalityBoer, Jolanda M. A.; Feskens, Edith J. M.; Monique Verschuren, W. M.; Seidell, Jacob C.; Kromhout, DaanAuthor Information From the 'Department of Chronic Disease Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands; 'Division of Human Nutrition and Epidemiology, Wageningen Agricultural University, Wageningen, The Netherlands; The Netherlands Institute for Health Sciences, Rotterdam, the Netherlands; 'Division of Public Health Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands. Epidemiology: November 1999 - Volume 10 - Issue 6 - p 767-770 Free Abstract We investigated the impact of family history of myocardial infarction on 12-year coronary heart disease mortality. Men and women with a family history had an increased risk for coronary heart disease death, irrespective of other risk factors (RR = 1.58; 95% CI = 1.17–2.13 and RR = 2.12; 95% CI 1.11–4.05, respectively). Women with a family history seemed to be more susceptible to the detrimental effects of smoking; not to the effects of other risk factors. We found no effect modification by family history in men. (Epidemiology 1999 © 1999 Lippincott Williams & Wilkins, Inc.