BRIEF REPORT: PDF OnlyA Case-Control Study of Mesothelioma and Employment in the Hawaii Sugarcane IndustrySinks, Thomas1; Goodman, Marc T.2; Kolonel, Laurence N.2; Anderson, Bruce3Author Information 1National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 2Cancer Research Center, University of Hawaii, Honolulu, HI 3Hawaii Department of Health, Honolulu, HI. Epidemiology: July 1994 - Volume 5 - Issue 4 - p 466-468 Free Abstract We conducted a case-control study of 93 mesothelioma cases and 281 cancer controls to determine whether sugarcane workers exposed to biogenic silica fibers were at increased risk of mesothelioma. We found no important excess risk of mesothelioma in sugarcane workers [odds ratio (OR) = 1.3; 95% confidence interval (CI) = 0.4–3.8] when we excluded all control subjects with cancer of sites suspected of being associated with asbestos exposure. We could not identify any sugarcane workers who developed mesothelioma and worked in jobs where high exposure levels to biogenic silica fibers have been measured. We did confirm that mesothelioma risk in Hawaii is associated with probable occupational asbestos exposure. Work at the Pearl Harbor Naval Shipyard was associated with a 10-fold increase in mesothelioma when we excluded controls with cancer of sites related to asbestos exposure (OR = 10.1; 95% CI = 2.6–56.6). Work in the medical industry was also associated with an unexpected increased risk for mesothelioma (OR = 4.2; 95% CI = 1.2–15.5). © Lippincott-Raven Publishers.