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Friday, February 16, 2018

A blood test that measures protein levels released from the brain into the blood may help predict which patients have intracranial lesions after concussions or mild traumatic brain injuries, according to the U.S. Food and Drug Administration, which approved the test this week. Developed by Banyan Biomarkers, the blood test measures ubiquitin c-terminal hydrolase L1 and glial fibrillary acidic protein and predicts which patients may have intracranial lesions visible by CT scan, possibly preventing unnecessary imaging and radiation exposure to patients, the FDA said.

The FDA evaluated data from a multicenter, prospective clinical study conducted by the U.S. Department of Defense and sponsored by Banyan of 1,947 blood samples from adults over 18 with suspected mild TBI or concussion and a Glasgow Coma Scale score of 9-13. Those samples were compared with CT scan results. The Banyan Brain Trauma Indicator was able to predict the presence of intracranial lesions on a CT scan 97.5 percent of the time and their absence 99.6 percent of the time. Results from the blood test are available within three to four hours, the FDA said.

The test was reviewed under the FDA's De Novo regulatory pathway for low- to moderate-risk devices that are novel and for which there is no similar device is marketed. (FDA, Feb. 14, 2018; http://bit.ly/2HoNpl1.)

Nearly 50,000 people died from TBI in 2013, according to the U.S. Centers for Disease Control and Prevention. Approximately 2.8 million TBI-related emergency department visits, hospitalizations, and deaths were recorded in the United States that year. Seventy-five percent of TBIs each year are mild or concussions, and a majority of patients with concussion symptoms have a negative CT scan, according to the FDA.

The Department of Defense reported on its website that 15,501 members of the military experienced mild TBI in just the first three quarters of 2014, 83.5 percent of all military traumatic brain injuries. (U.S. DOD, Dec. 1, 2014; http://bit.ly/2ENWGoc.) "A blood test to aid in concussion evaluation is an important tool for the American public and for our Service Members abroad who need access to quick and accurate tests," said Jeffrey Shuren, MD, the director of the FDA's Center for Devices and Radiological Health.

The study's trial record is available at http://bit.ly/2HowLC6.


Tuesday, November 7, 2017

BY JONATHAN D. MILLER, MD

The seat belt sign chimes again. Pinned between two strangers for hours, I silently wish for a brief reprieve—beverage service or a chance to hobble toward the back of the plane to stretch. But, no, the captain has turned on the seat belt sign again. She's the boss, and I trust her with my safety, regardless of how uncomfortable I might be.

Many analogies have been drawn between the seemingly different worlds of aviation and medicine over the years. Many have continued to look for similarities since Dr. Atul Gawande wrote The Checklist Manifesto. One of the best lectures I've heard was from fellow emergency physician Dr. Joe Novak who spoke at the ACEP Scientific Assembly about combat aviation paradigms" comparing our craft and our training to that of an Air Force fighter pilot. As a pilot and emergency physician, I think there are more comparisons yet to be made.

The aviation industry is plagued with bureaucracy. It makes sense to the lay passenger that the government ensures our safety. Colgan Air flight 3407 tragically crashed in Buffalo in 2009. This led Congress to raise the minimum number of hours required to fly as a co-pilot from 250 to 1,500 hours before being eligible for hire. The new requirements have led to a pilot shortage in our country, although this rule was developed with input from the Airline Pilots Association, a union with 52,000 members.

Medicine is no stranger to oversight. Joint Commission visits and an onslaught of quality metrics to report on is a never-ending plight for hospitals and physicians. Yet, unlike pilots, we have no voice. Sure, the American Medical Association and specialty colleges like the American College of Emergency Physicians exist to express concerns for physicians throughout our country, but the past decade of government turmoil brought down on physicians would suggest that having a few lobbyists looking out for us isn't enough.

Pilots would not follow a new operating procedure that made flying unsafe. Their union would speak up. The government dragged their feet when iPads became the new way to keep charts and airport information handy. The Federal Aviation Administration said they would need to do "more research" before agreeing that its use would be safe in flight. Pilots knew that this technology would save fuel and paper, reduce pilot workload, make flying safer, and save the pilot from dragging a 40-pound bag of charts through every airport. Many pilots still used the technology before given the official go-ahead. They are the experts, not the bureaucrats. They knew having charts readily accessible on an iPad when struggling to fly through difficult weather made the flight safer. So they did it. The FAA eventually saw the light, and now having an iPad in the cockpit is ubiquitous.

Pilots had work-hour restrictions long before medical residents did. Some experts doubt the ACGME requirements have resulted in increased safety at academic institutions, but aviation authorities certainly believe in their utility. The FAA (not the pilot experts) attempted to make the rules even more stringent in 1995, requiring increased periods of rest and less time in the cockpit each day. There can be too much of a good thing, and the pilots rang out! Union and industry pundits had a seat at the table. The increase in policymaking oversight was stifled. Every time it comes up again, it's a committee of pilots and doctors (experts in the physiology of flight) who have a voice. It is not a committee of congressmen on Capitol Hill.

Why don't physicians act in the same manner? Recently I was told by an administrator that nurses and providers (administrators never call us doctors anymore) couldn't have cell phones in patient care areas. I keep many resources on my phone. Paucis Verbis cards, Epocrates, Pedi-Stat, and other cell phone apps are integral to my practice of emergency medicine. The other option is to carry around a stack of outdated pocket cards, which would make a seasoned emergency physician look more like a third-year medical student with their overburdened white coats. I told her I would continue to use my phone. I am the expert in patient care. I know that having these resources helps me provide excellent, up-to-date care. Speak up! You are the expert.

North America is beginning to see a pilot shortage crisis. It is only expected to worsen. The experience required to be eligible for a co-pilot position increased sixfold in 2009. The typical debt incurred to become a pilot is well over $100,000 unless one joins the military. Once done with that, you suffer through endless low-paying jobs before you make it. Then, your first job at the regional airlines pays quite poorly, although slightly more per hour than you made during your residency. Eventually, you make a healthy salary after gaining experience and seniority. Sound familiar to the long road toward a career in medicine that you followed?

How are airlines fixing the pilot shortage? Many are beginning to create their own training programs. Train with them, and you are guaranteed a job—with less debt in the process. Remove financial barriers toward education, and more eligible pilots will come knocking. Airlines understand economics better than hospital systems and insurance companies. If you pay more, they will come. Bonuses and increased wages are also beginning to result in more aviators being willing to take on the financial burden of becoming an airline pilot.

Like the airlines, we are facing a physician shortage in our country. The debt incurred by undergraduate and medical education is staggering. Much like a pilot, one has the option of joining the military to decrease the burden of debt. Doctors who don't join the military must endure a decade of training with hundreds of thousands of dollars in debt. We accept this despite an ever-decreasing salary. In fact, it's difficult to imagine another profession where you get paid less the longer you work.

Perhaps we should follow the airlines' lead. What if hospital systems paid for residencies instead of Medicare and Medicaid funding them? What if I train with Kaiser, and then Kaiser pays my medical school costs and pays my salary during residency? I become a well-oiled Kaiser machine in the process who then signs a contract to work for a given number of years. Money talks. Paying board-certified physicians what they deserve and what they've previously made makes sense. No doctor should have to spend two decades paying off their loans.

Pilots don't have at-risk funds. What if 15 percent of a pilot's paycheck was held at ransom, given to them only if their passengers' satisfaction was in the 90th percentile and if they had on-time arrivals 95 percent of the time. That will not happen. Do you think that would lead to safe decision-making? No, it would result in airline accidents. It would result in death.

Pilots don't control the weather. They can't control the fact that the airlines they work for took away meals, peanuts, and that extra inch of leg room. The pilot instead focuses his energy on being a consummate professional and getting people safely to their destinations. Why aren't physicians more like pilots? We too cannot control the climate in our workplace. Sometimes, the ED gets busy. Wait times will rise when several critical patients arrive at once. That's OK. Period.

When saving a life, the patient with an ankle sprain can wait. Unfortunately, all too commonly contracts are being written with the premise that physicians must do X, Y, and Z to get the reimbursement that was, at one time, rightfully theirs.

It's time to take control of our aircraft. Thinking back to that uncomfortable flight, I had a lot to complain about. I was hungry. I was tired. I was bored. I got home three hours later than expected. But when I take a step back, I realize just how amazing it all was. I flew from coast to coast, over and around major thunderstorms, in a period of four hours. I just left my home in the Northwest, and this evening I'm having a family dinner in Alabama. I'm not using FaceTime to say hello to my mom; I'm using a hug. It's incredible. It's easy to be increasingly negative in a society that values speed, ease, and a burden-free world, but it's much easier to see just how good we have it when you look at the view from 40,000 feet. The emergency department is no different.

Why don't our colleagues, our government, and our administrators look at medicine in the same way? Yes, there was a delay in getting you to your room. Yes, the food is terrible or nonexistent. Yes, the gurney is less comfortable than a plush recliner. But at the end of the day, a trip to the emergency department is as incredible as a flight across the country, despite its inadequacies.

A patient is distressed. He has had pain for a week. A board-certified physician decreases his pain, listens to their worries, diagnoses his ailment, and advocates for his treatment. What might take weeks to work up in the outpatient world takes hours to work up in the ED. Where at people at one time died due to injury, now they arrive and have their lives saved in an immediate fashion by experts.

We are the captains of our ship. We know what is best for our patients and for health care. When a pilot decides to delay a flight due to dangerous lightning or a warning light in the cockpit, no passenger has the audacity to walk to the front of the plane to tell them to get going. The CEO of the airline doesn't patch into the radio to tell them to depart immediately because of the growing number of passengers sitting at the gate. Believe it or not, there is safety in paternalism! We trust the pilot to get us to our destination without harm. We acknowledge they have more experience than we do. If that means we must wait an extra hour or an extra day, we comply.

I believe it is time for us to act more like pilots. If you don't need an MRI scan of your head, I shouldn't order it just to make you happy. If I spend an hour in the critical care bay, I shouldn't get reprimanded by administration for decreased throughput. They should thank me for saving a life and for doing what I was trained to do. They shouldn't chastise me or lessen my pay because someone with a cold waited for three hours. My skill as an emergency physician should not be tethered to a wait time on a billboard. The government shouldn't judge me by how well I treat someone's pain. Increased workload and alert fatigue through our EMRs (our version of the cockpit) has become unsafe and overly complicated, and it has diminished the human aspect of medicine that many of us sought when we chose our profession. Why should I be forced to spend more time in front of a computer screen under the guise of meaningful use when it has never been proven to be meaningful?

Many people love to talk about physician burnout. This is simply a synonym for its true meaning: physician disempowerment. Let's call it what it is. It's time we speak up. It's time we take the controls of the craft we spent so many years learning. It's time we have a seat at the controls. It's time we unionize, just like pilots have.

Dr. Miller is a clinical instructor with the University of Washington and an attending emergency physician practicing in Boise, Idaho. He also works as a critical care air transport physician and EMS director with the Idaho Air National Guard.


Wednesday, October 4, 2017

BY FRANK DEL VECCHIO, MD

When I first heard of the shooting in Las Vegas a few days ago, it sounded as if only a few people were injured. I was preparing for bed, but as soon as I realized the scope of the incident, I went immediately to the emergency department. I ran several red lights as ambulances do, exceeded speed limits by a factor of 2+, and was quickly waved through police barricades when I showed my hospital ID.

I would like to say that I heroically saved dozens of lives by performing numerous invasive bloody procedures, but that was not the case. Most of the serious cases were already handled when I got there. We had one DOA, and all the others are expected to survive, but many will have permanent injuries.

When I arrived, I was immediately struck by how quiet it was. Nothing moved me more than how patients with horrific injuries heroically suffered in silence while the staff worked diligently to care for all. They knew we would get to them as soon as possible and in order of priority. None of the providers yelled or so much as raised their voices. They walked briskly, but never ran. With the exception of one neurosurgeon who did not want to be bothered, specialists and ancillary services responded quickly and efficiently.

It was truly an inspirational scene, once you could get beyond the depravity of what just happened.

The worst cases I saw were an 18-year-old girl with a spinal injury who will be permanently paralyzed, and a young man whose hip was pulverized and femoral artery lacerated. He may keep his leg, but probably will never walk well again.

I didn't perform any dramatic invasive procedures, but I would like to think that coordinating complex evaluations among the surgeons, technicians, and nurses was just as life-saving.

I offered many reassurances to patients as honestly as I could. I touched many foreheads, gently placed my cheek on a few, and gave hugs to others, including family members. It was all graciously and emotionally received.

It was deeply moving to see the help offered to others by non-medical people. Bystanders used makeshift stretchers to carry people out of harm's way, drivers allowed bloodied victims to pile into their nice cars for transport to the hospital, and pickup trucks were also used to transport more serious victims. Long lines, up to six hours, formed with those waiting to give blood. Many delivered food and drink to the donors.

Out of evil and chaos came goodness and beauty.

I believe there is a God, but even if you don't and even if you are correct, there is God-like charity in all of us should we choose to practice it.

I felt emotionally detached from it all, until the following day, at which time I must admit, I needed a few moments alone.

We may never know what motivated the perpetrator, but he was obviously a tortured soul. I believe that almost all human beings are innately good. Children raised in loving and supportive environments, even with disparate financial resources, will almost always become loving and contributing adults. Providing children with a moral compass, regardless of religious beliefs, is an important part of the same process.

Beyond raising children, we can all play a part in this. Please consider donating your time to charities, especially those working with underprivileged children. Also, set up affordable automatic monthly donations to the charities of your choice. Remote Area Medical (https://ramusa.org), Safe Nest (https://safenest.org), and Three Square, a service feeding poor children (https://www.threesquare.org), are among my favorites.

Savor your relationships with family and friends and those things you enjoy. In less than a second, it can all be taken away from you.

Spread goodwill and generosity to others, every day, even in small ways. Be kind to others, even when they don't deserve it.

Dr. Del Vecchio is an emergency physician in Las Vegas and a retired U.S. Navy captain and flight surgeon.​


Thursday, September 28, 2017

BY STEPHEN HAIRE, MD

​Rapidly treating sepsis patients with antibiotics is absolutely vital to their survival. Even an hour or two of delay could cost a patient his life. But as U.S. hospitals are striving to implement effective sepsis protocols, many feel torn between that and a parallel and equally important national effort—our need to reduce antibiotic overuse and misuse, which is a primary driver of our growing antibiotic resistance problem. Ironically, we at Morton Plant Hospital BayCare Health System (MPMHC) learned that these two goals don't have to be at cross-purposes. The key to optimizing these essential goals is the biomarker procalcitonin or PCT.

No one has ever said to me in my 20 years as an emergency physician, "Doctor, I think I may have sepsis." In fact, more than 40 percent of those surveyed said they had never heard of the term "sepsis," according to a 2015 survey by the Sepsis Alliance. (
http://bit.ly/2xaoL5v.) Have we done a poor job explaining this syndrome? Perhaps, but sepsis is a difficult concept to convey. It's always secondary to a preceding condition, such as pneumonia and urinary tract and gastrointestinal infections. But the fact remains that when these patients die, sepsis is what usually kills them. As a consequence of patients living longer with serious chronic conditions and the crisis of antimicrobial resistance, the incidence of sepsis is growing and affecting younger and younger patients. (JAMA 1995;273[2]:117.)

Our ED, ICU, pharmacy, and other departments decided in 2008 to see what we could do to reverse these trends within our health system. The sepsis protocol at MPMHC is built on a team approach that involves every clinical department and caregiver who comes into contact with a potential sepsis patient from the ED until discharge.

 sepsis fig 1.JPG

Our goal was simple: We wanted to pull patients into our sepsis protocol as early in the sepsis inflammatory cascade as possible. Interventions that save lives are thoroughly proven and documented: Fluids, antibiotics, and vasopressors can save the majority of patients. This is not the problem. The problem is discerning who to put on this track with a syndrome that shares symptoms with many other conditions. Only sepsis accelerates with terrifying speed and morbidity, however.

Figure 1 illustrates how fast septic patients can deteriorate. We could save many of them if we could identify sepsis patients before the initial organ failure. (
JAMA 1995;273[2]:117; Critical Care Med 2001;29[7]:1303; Intensive Care Med 2002;28[10]:1440.) We included the biomarker procalcitonin (PCT) in our protocol so we could utilize the earliest possible signals that a patient is at risk for sepsis because it provides us with vital clues that often go undetected until the sepsis cascade is well underway.

Sepsis Defined
The 1992 guidelines from the American College of Chest Physicians and the Society of Critical Care Medicine defined systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, and septic shock. (Chest 1992;101[6]:1644.) SIRS is defined as a patient having two of the following four symptoms:

n Temperature higher than 38°C (100.4°F) or lower than 36°C (96.8°F)
n Heart rate above 90 beats per minute
n Respiratory rate higher than 20 breaths per minute or arterial carbon dioxide tension (PaCO2) of less than 32 mm Hg
n Abnormal white blood cell count (>12,000/µL or <4,000/µL or >10% immature [band] forms)

Because SIRS is nonspecific with infection as its root cause, along with other noninfectious etiologies such as ischemia, inflammation, and trauma, the definition of sepsis depends on the diagnosis of SIRS plus a new set of criteria:

n Sepsis is defined as SIRS plus a new infection.
n Severe sepsis is sepsis plus organ dysfunction.
n Septic shock is severe sepsis plus hypotension that persists despite fluid resuscitation or lactate great than 4.

​ED Sepsis Alert
Our sepsis protocol allows emergency physicians to screen for sepsis and to place likely septic patients on a track designed to reduce its effects of sepsis and make these patients better sooner. This begins in the ED, but the protocol is a team approach that relies on those with skills and experience across the entire treatment continuum for a septic patient. The team includes registration, ED and ICU nurses, intensivists, emergency and critical care physicians, respiratory therapy, and unit clerks.

We integrated our new screening tool with our EMR software. We evaluate all patients for sepsis, and roughly 30 to 40 patients per day are detected by our sepsis screening tool in the ED. Two to three of those patients end up on the sepsis protocol based on that screening process. Our screen looks at lactate level, blood pressure, tachycardia, CBC, BNP, and PCT levels.

PCT is the key to the success of this screening program. An elevated PCT is a powerful indicator that a severe bacterial infection has occurred and that sepsis is possible. A normal PCT score, particularly one that remains normal for several days, allows us to look for other etiologies sooner than we would have without PCT. Once we identify a patient with sepsis, the emergency physician initiates the sepsis alert, which is sent to the operator and issued as a stat page to the admitting team and the transfer center that tele-tracks bed control. The administrator on duty is also made aware of the patient, and will assist in the ED or the ICU if the patient has already been transferred. The stat page also goes to the ICU charge nurse and the respiratory therapist on duty. Labs are done stat so the turnaround time is efficient. We also draw blood cultures and send these to the lab.

sepsis fig 2.JPG

Rapid Antibiotics
A study by Kumar, et al., documented the correlation between delayed antibiotics for those in septic shock and mortality. (Crit Care Med 2006;34[6]:1589.) Figure 2 is one of the most compelling graphics that explains the horrible and all too predictable consequences of delayed treatment in septic shock patients. Kumar concluded that the survival rate for effective antibiotics in the first hour of documented hypotension was 79.9 percent, but this drops dramatically with each passing hour. The survival rate with antibiotics five to six hours post-documented hypotension was 42 percent. Survival plummets to 25.4 percent by hours nine to 12. In fact, each hour of delay in giving antibiotics to these patients translated into a decrease in the survival rate of 7.6 percent. The median time to effective antibiotic delivery was six hours, which has a mortality rate of nearly 60 percent.

Procalcitonin testing can help you stay ahead of this vicious spiral. PCT elevation is very responsive to bacterial challenge so the biomarker begins to rise almost immediately. Figure 3 shows that PCT levels of 0.05 ng/mL or below represent the normal range; 0.05-0.5 ng/mL is indicative of a local infection; 0.5 to 2.0 ng/mL indicates a systemic infection; 2-10 ng/mL is severe sepsis, and anything over 10 ng/mL is strongly indicative of septic shock. PCT does not respond at all to viral or fungal infections, which is why we began to use it as a tool to assist in antibiotic stewardship several years ago.


sepsis fig 3.JPG
Overusing Antibiotics
Initiating our sepsis response in the ED made us quickly realize that there was great value in testing for PCT in the ED, regardless of whether the patient had a blood infection or sepsis. A 68-year-old man, for instance, was admitted to our emergency department with lethargy, headache, neck stiffness, disorientation, and rising blood pressure. The patient was a smoker with type 2 diabetes and a past history of cardiac issues, including a heart attack. Tests showed a high white blood cell count, normal cardiopulmonary function, and negative neurological exam results.

The initial PCT level taken in the ED was low, and it remained normal for several days. His symptoms and normal PCT level led the ICU team to look for other possible causes. A lumbar puncture revealed that he was suffering from viral meningitis. Thanks to a normal PCT level that remained well within the normal range for several days, antibiotic exposure was dramatically limited in this patient. The viral meningitis was effectively treated, and he was discharged.

sepsis 4.JPG

Another patient, an elderly man, arrived in the ICU via the emergency department, presumed to have pneumonia, suggested by a bilateral perihilar infiltrates. The patient had a fullness of the right hilum, which was possibly vascular but also suspicious for lymph node enlargement. Follow-up clearance was recommended to ensure no underlying pathology. His white blood cell count was high, so he was treated aggressively with antibiotics and fluids. He remained symptomatic of pneumonia for three days, and his physicians began to consider other causes, so they took a second look at his serial PCT levels. Figure 4 shows his WBC, troponin-L, and PCT levels over three days. His initial ED PCT level was 0.10 ng/ml—well within the normal range. It never exceeded 0.15, also normal, over the course of three days. PCT made it clear that we were not likely dealing with an infection. A chest x-ray taken on the third day confirmed heart failure. Antibiotics were stopped, and he was successfully treated for this cardiac crisis.

The negative predictive value of PCT cannot be understated. Without PCT, we may never have realized the patient was suffering from heart failure. Three days of antibiotics are three days too many for a patient without an infection, this patient may have been treated for
a week, possibly 10 days were it not for the information provided by PCT.

Serial PCT testing—starting in the ED—is now central to our sepsis protocol and our antibiotic stewardship program. The test provides us with much more confidence when deciding whether to start antibiotics or when looking for a noninfectious underlying cause of the patient's symptoms. It also is of enormous benefit in discontinuing antibiotics. PCT closely follows the trajectory of a severe bacterial infection, so we use an algorithm based on the percentage decrease in PCT from its highest measurement to help us determine when we can safely begin to curtail IV antibiotics. Until PCT, most U.S. hospitals used the football score approach to antibiotic duration: 3, 7, 10, or 14 days. Virtually no evidence supports this approach, however. We must avoid giving antibiotics to patients who are without bacterial infections in this age of rampant antibiotic resistance, but we also must reduce or discontinue powerful IV antibiotics when the patient's infection has abated.

I would like to thank Devendra Amin, MD, the medical director for critical care services at Morton Plant Hospital, who spearheaded the effort to bring PCT testing to our hospital, who has worked tirelessly to help educate other clinicians at Morton Plant and across the country, and who helped me collect data for the case studies presented in this article.

haire.JPG 
Dr. Haire is an emergency physician and the medical director at Morton Plant Hospital, BayCare Health System, in Clearwater, FL, the chairman and CEO of Bay Area Emergency Holdings Corp., and the chairman of the EMS advisory board for Pinellas County. He disclosed that he wrote this article for bioMérieux, though he did not receive compensation for it. He does, however, receive remuneration for bioMérieux speaking engagements.

Tuesday, September 12, 2017

BY MARTHA ROBERTS, ACNP, PNP

News stories flooding social media, the internet, and television sparked outrage after a police officer's body camera video showed the arrest of a Salt Lake City, UT, nurse, Alex Wubbels, in July. Ms. Wubbels, who said she was protecting the rights of her unconscious patient, was arrested for obstruction of justice for refusing to provide the police with blood samples without a warrant, the patient's consent, or a stated intent to arrest the patient. Recordings of the scene showed Ms. Wubbels being dragged out of the hospital by a police officer. (NBC News. Sept. 4, 2017; http://nbcnews.to/2xbHZYM.)

This story generated questions about police brutality against patients and health care workers involved in their care, as well as about the communication between medical providers and the police. Patients and health care workers are at risk of police maltreatment, and it is a growing threat and issue.

Police brutality and medical negligence are concerns nationwide, like the case of Freddie Carlos Gray Jr., a 25-year-old African-American man arrested on April 12, 2015, by the Baltimore police for possessing what the police alleged was an illegal switchblade. (PBS NewsHour. May 1, 2015; http://to.pbs.org/2w8rqb6.) When Mr. Gray was being transported in a police van to central booking, he became comatose and died from severe neck and spinal cord injuries.

The medical investigation found that Mr. Gray had "sustained the injuries while in transport," and did not receive timely medical attention after he had asked for help and said twice that he couldn't breathe. (CNN. April 24, 2015; http://cnn.it/2w8u1So.) The media and the courts questioned the police's role in Mr. Gray's death, and the officers involved in the case were later convicted of second-degree murder and manslaughter for delaying Mr. Gray's medical care. (New York Times. May 1, 2015; http://nyti.ms/2w7N5A0.).

At least 4,813 people died in the process of being arrested by local police between 2003 and 2009, according to data from the Bureau of Justice Statistics. (http://bit.ly/2w7U1gN.) The bureau classified 2,876 of those deaths as law enforcement homicides, and 1,643, or 57.1 percent, of those were minorities. (http://bit.ly/2w7Hiup.) Police brutality isn't limited to beatings, Tasers, shackles, trauma, shootings, and wrongful arrests. Assault and battery are also issues. In Mr. Gray's case, he was placed in metal ankle braces even though he was shown to be completely motionless on a cell phone recording. (The Baltimore Sun. May 20, 2015; http://bsun.md/2w7NfaO.)

It is difficult to advocate for patients when the police are involved. Sometimes the patient does not get timely medical care, or their medical rights are not protected. Ms. Wubbels was advocating for a patient who was not under arrest, and she ended up in handcuffs.

As emergency department providers, we often see patients who are in the ED to be cleared to go back to jail or those who may be involved in complicated judicial matters. There are times when our patients are drunk, high, hostile, and incorrigible. But what about those who need further evaluation or whose medical rights are ignored? This includes patients from whom you must collect belongings or even blood samples. How do we protect these patients and ourselves?

We must be aware of what happens in the police's field and in ours. All patients brought in by the police deserve a full examination, privacy, an appropriate treatment plan, and the protection of their rights. Proper protocols must be followed, especially if the rights of the patients are being denied. We cannot step between the law and official police business, but we can advocate for appropriate care. You must always be concerned for the safety of the patient.

The bottom line is patients' rights are a serious matter and should always be on your radar, according to Ms. Wubbels. "The only job I have is to keep my patient safe," she said at a press conference. "Blood is your blood. That is your property. When a patient comes in a critical state, that blood is extremely important, so I don't take it lightly."(CBS. Sept. 1, 2017; http://cbsn.ws/2w7LudD.)​

Ms. Roberts is an acute care nurse practitioner at Medstar Montgomery Medical Center in Olney, MD, an adjunct faculty associate and clinical instructor of nursing at the Malek School of Health Professions, Marymount University in Arlington, VA.