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Complex Myograph: evaluation of a diagnostic device and standard values for force, velocity and working capacity of the muscle in-vivo: A-132

Rahe-Meyer, N.; Winterhalter, M.; Gross, M.; Zuk, J.; Piepenbrock, S.

European Journal of Anaesthesiology: May 2005 - Volume 22 - Issue - p 36–37
Ambulatory Anaesthesia

Department of Anaesthesiology, Hannover Medical School, Hannover, Germany

Background and Goal of Study: With the newly developed Complex Myograph it is possible for the first time to determine the individual muscular contraction force, velocity, and work at the point of optimum muscle prestretching. This trial investigates the reproducibility and the precision of the measuring method. Physiological standard values for force, velocity and work are presented.

Materials and Methods: The experiments in this study are in-vivo conducted on musculus adductor pollicis. A self-developed device brings the physiological rotation axle in a congruent position with the axle of the apparatus, holds it there, and brings the muscle on the optimum of pre-stretching. There constant counter-forces can be attached to the muscle and the muscle can be stimulated indirectly. The contraction are measured with three mechanical sensors. For the reproducibility trial we performed a succession of 500 tests with 5 test subjects. The results of amplitude and deviations were analysed with two-way factorial variance analysis by UNIANOVA in SPSS. For collecting the standard values measurements on 700 healthy test subjects were conducted.

Results and Discussions: The precision of the measuring device was 98.6%, which expresses the experimental and measuring fluctuations, cleared from the natural changes of muscular force of an individual test object through time. After single supra-maximal nerve stimulation was the mean for maximal force 9.51 N (±2.42), for maximal velocity 175.23m/s (±18.92) and for maximal work 43.47 mJ (±15.04).

Conclusion(s): With the Complex Myograph the in-vivo efficiency of the muscular elements can be characterised for the first time, in particular the complex mechanical capacity. A high precision and reproducibility is reached and standard values are established. Important steps in direction of a clinical, pathophysiological diagnostic device for innate or acquired muscular diseases are made.

© 2005 European Society of Anaesthesiology