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Different EEG analysis of low flow xenon anaesthesia during laporoscopic surgery

Lickvantzev, V.; Soubbotin, V.; Petrov, O.; Volovik, A.; Burov, N.

European Journal of Anaesthesiology: 2000 - Volume 17 - Issue - p 20
European Society of Anaesthesiologists; 8th Annual Meeting with the Austrian International Congress; Vienna, Austria, 1-4 April 2000

Department of Anaesthesiology, Surgery Institute N.A. Vishnevsky, Moscow, Russia

Abstract A-65

Background and goal of study: Zenon is well known as a good anaesthetic agent [1, 2]. The goal of the study is analysis of changes of bispectral index of EEG (BIS) and informational saturation of EEG (INEEG) [3] during xenon anaesthesia.

Materials and methods: We studied 24 patients (ASA I-II) undergoing abdominal laporoscopic technic surgery. After induction (propofol 1.8 ± 9.3 mg kg−1 i.v.; tracrium 0.5 mg kg−1 i.v. + xilocain spray −10% local) and intubation anaesthesia was maintained with 70 ± 1% xenon and O2 (close system) supplemented with fentanyl 1.48 ± 0.71 μg kg−1 h−1 i.v. We used low flow technique. Fresh flows were Xe-0.14 ± 0.02 L min−1. O2-0.25 ± 0.05 L min. Duration of anaesthesia was 58-270 min. BIS was recorded by the apparatus A-1000 (Aspect Medical System Inc., USA), the INEEG calculated by computer on a basis of our original programs [3]. Data were analysed by independent Student's t-test and correlation analysis.

Results: Data are mean ± SD. TABLE



Fentanyl administration during increasing of the INEEG up to 57 ± 2 and BIS up to 59 ± 3 caused by surgical stimulation results in decreasing of both investigation parameters to Xenon 70% level. The correlation between investigation parameters was 90%.

Conclusion: The results indicate that INEEG and BIS have a good correlation during xenon anaesthesia, and xenon in 70% guarantees good anaesthesiologocal conditions for abdominal laporoscopic surgery.

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1 Luttropp HH, Thomasson R, Dahm S et al. Acta Anaesth Scand 1994; 38(2): 121-125.
2 Burov NE, Kasatkin luN, Ibragimova GV et al. Anesth Rean 1995; 4: 57-60.
3 Lickvatzev V, Petrov O, Sitnikov A et al. Br J Anaesth 1998; 80(Suppl. 1): A126.

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The abstracts published in this supplement have been typeset from camera-ready copies prepared by the authors. Every effort has been made to reproduce faithfully the abstracts as submitted. However, no responsibility is assumed by the organisers for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of methods, products, instructions or ideas contained in the material herein. Because of the rapid advances in medical sciences, we recommend that independent verification of diagnoses and drug doses should be made.

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© 2000 European Society of Anaesthesiology