Online ArticlesAltering Pulse Frequency to Enhance Stimulus Efficiency During Electroconvulsive TherapyRavishankar, Vinutha MBBS; Narayanaswamy, Janardhanan C. MD; Thirthalli, Jagadisha MD; Reddy, Y.C. Janardhan MD; Gangadhar, Bangalore N. MDAuthor Information From the Department of Psychiatry, National Institute of Mental Health And Neurosciences (NIMHANS), Bangalore, India. Received for publication July 25, 2012; accepted August 21, 2012. Reprints: Janardhanan C. Narayanaswamy, MD, Clinical Research Associate, Translational Psychiatry Laboratory, Neurobiology Research Center, NIMHANS, Bangalore-560029, India. (e-mail: [email protected]) The authors have no conflicts of interest or financial disclosures to report. The Journal of ECT: March 2013 - Volume 29 - Issue 1 - p e14-e15 doi: 10.1097/YCT.0b013e31827032b0 Buy Metrics Abstract Stimulus parameters like pulse amplitude, shape, width, and train frequency exert unique neurobiological effects. Herewith, we report the case of a patient in whom seizure induction was not possible with conventional stimulus parameters using bitemporal electroconvulsive therapy. She had successful induction of seizures with reduced charge rate. This strategy may be considered as an additional measure of improving the chances of seizure induction during electroconvulsive therapy, and it may be seen as a practical consideration. © 2013 Lippincott Williams & Wilkins, Inc.