Online ArticlesEffects on Intracranial Pressure of Electroconvulsive TherapyDerikx, Roy L.E. MD*; van Waarde, Jeroen A. MD†; Verwey, Bastiaan MD, PhD†; van der Mast, Rose C. MD, PhD‡Author Information From the *Admiraal de Ruyter Hospital, Vlissingen; †Rijnstate Hospital, Arnhem; and ‡Leiden University Medical Center, Leiden, The Netherlands. Received for publication October 30, 2011; accepted January 26, 2012. Reprints: Jeroen A. van Waarde, MD, Rijnstate Hospital, Department of Psychiatry (B0V1), P.O. Box 9555, 6800 TA Arnhem, The Netherlands (e-mail: [email protected]). The authors have no conflicts of interest or financial disclosures to report. The Journal of Electroconvulsive Therapy: June 2012 - Volume 28 - Issue 2 - p e23-e24 doi: 10.1097/YCT.0b013e31824d9b69 Buy Metrics Abstract Electroconvulsive therapy (ECT) is thought to raise intracranial pressure (ICP) after an increase of blood pressure. In depressed patients (n = 17) treated with ECT, using transcranial Doppler, pulsatility index (PI; as indicator of ICP) and blood pressures were prospectively measured. The highest PI was measured just after anesthesia induction and muscle relaxation. Blood pressures increased significantly after succinylcholine and thereafter but did not correlate to PI. After anesthesia and muscle relaxation, the PI was higher than just before ECT; the PI was lower during seizure activity and after ECT. Therefore, ECT itself seemed not to raise ICP. © 2012 Lippincott Williams & Wilkins, Inc.