Case ReportsTics as Signs of Catatonia: Electroconvulsive Therapy Response in 2 MenDhossche, Dirk M. MD, PhD*; Reti, Irving M. MBBS†; Shettar, Shashidhar M. MD*; Wachtel, Lee E. MD‡Author Information From the *Department of Psychiatry, University of Mississippi Medical Center, Jackson, MS; †Department of Psychiatry and ‡Kennedy Krieger Institute, Johns Hopkins School of Medicine, Baltimore, MD. Received for publication October 3, 2009; accepted November 7, 2009. Reprints: Dirk M. Dhossche, MD, PhD, Department of Psychiatry, University of Mississippi Medical Center, 2500 N State St, Jackson, MS 39216 (e-mail: firstname.lastname@example.org). No financial support was received for the study. The authors have no proprietary or commercial interest in the study. The Journal of ECT: December 2010 - Volume 26 - Issue 4 - p 266-269 doi: 10.1097/YCT.0b013e3181cb5f60 Buy Metrics Abstract Objectives: Tics have rarely been described in catatonia although tics are sudden and nonrhythmic variants of stereotypic or repetitive movement abnormalities that are considered cardinal symptoms of catatonia. We describe 2 men with tics and self-injurious behavior, who met criteria for catatonia. One patient met criteria for autism. Case Reports: We reported 2 new cases and performed a literature review using PubMed to identify other cases of tics that were treated with electroconvulsive therapy. Tics along with other catatonic symptoms and self-injurious behavior responded to electroconvulsive therapy in 2 men. Eight other patients with tics that were treated with electroconvulsive therapy were found in the literature. Catatonia was recognized in 4 of the 8 patients. Two patients met criteria for autism. Conclusions: Tics, with or without self-injurious behavior, may be signs of catatonia. Patients with tics or Tourette syndrome warrant assessment for catatonia. If catatonia is present, electroconvulsive therapy provides a safe but rarely used alternative to pharmacotherapy, psychosurgery, or invasive brain stimulation in the treatment of tics and Tourette syndrome. © 2010 Lippincott Williams & Wilkins, Inc.