Evidence-Based Practice

Introducing Good Evidence Matters (GEMs), a series that provides reviews of new and relevant original research publications for primary care providers. Studies are critically appraised and summarized by authors in order to provide valuable new information that can be easily consumed and shared. GEMs summaries include clear key takeaways along with transparent and to-the-point summarization of its methods, results, level of evidence and any bias or limitation. GEMs are the perfect read for busy clinicians to keep up with current research.

Aspirin, friend or foe of the healthy elderly?

Weighing the benefits of aspirin in primary prevention in diabetic individuals

Nonopioid analgesics as effective as opioids for acute pain?

PURLs

Priority Updates from the Research Literature (PURLs) is an FPIN series designed to alert practicing physicians about new discoveries that could cause them to change the way they practice and treat patients. Please review the PURLS Methodology document for information about the rigorous process by which FPIN identifies, evaluates, and publishes a PURL.

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Current Issue

June 2023 - Volume 26 - Issue 6

EDITORIAL

Compass points

DIVING FOR PURLs

More is not always better: low-dose IM ketorolac noninferior to high dose in moderate acute pain

Time to ginger up our antiemetics

Return to play? Put the screens away!

Efficacy and tolerability of combination pharmacologic therapy for treatment of unipolar depression

Cardiac risk with amphetamine use in older adults

Put a cast on it! Nonoperative management of acute Achilles rupture

IN DEPTH

Is there a difference in treatment outcomes between short (seven days or less) and long (greater than seven days) courses of systemic corticosteroids in patients with an acute exacerbation of COPD?

HELPDESK ANSWERS

Is elagolix an effective and safe option to decrease menstrual blood loss in patients with uterine fibroids and menorrhagia?

Does remote follow-up (by telehealth) after medication abortion result in more adverse outcomes compared with in-person follow-up?

Is there any benefit to statin therapy for prevention or treatment of preeclampsia?

In patients with acute decompensated heart failure, does BNP- or NT-proBNP-guided therapy during hospitalization improve outcomes compared with usual care?

Does eating eggs increase the risk of heart disease?

Does resistance training in patients with metabolic syndrome reduce cardiovascular risk factors?

Do traumatic brain injuries (TBI) in veterans increase the risk of getting dementia?

What is the effectiveness of antidepressants to treat tobacco use disorder?

Does SSRI therapy improve quality of life in adults with IBS?

Is there an increased risk of dementia with use of medications for overactive bladder?

Is transcutaneous electrical nerve stimulation an effective treatment for low back pain?

SPOTLIGHT ON PHARMACY

In patients with opioid use disorder receiving medication-assisted treatment, does short term use of opioids for pain control during hospitalizations increase the risk of relapse or significantly change subsequent maintenance doses?

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