HELPDESK ANSWERSAre probiotics effective for the prevention of upper respiratory infections in children?Davis, Trina J. MD; Volk, Bradford MDAuthor Information Group Health FMR Seattle, WA Evidence-Based Practice: October 2016 - Volume 19 - Issue 10 - p 22-23 doi: 10.1097/01.EBP.0000541537.21508.ae Buy Metrics Abstract EVIDENCE-BASED ANSWER It depends. Daily supplementation with at least 109 colony forming units (cfu) of either Lactobacillus rhamnosus GG or L acidophilus reduces the frequency of upper respiratory infections and the symptoms of fever and cough. When combined with Bifidobacterium lactis, such supplementation also reduces the occurrence of rhinorrhea (SOR: B, RCTs in Croatia and China). Supplementation with Bifidobacterium alone does not appear to decrease the frequency of upper respiratory infections (SOR: B, single RCT in Finland). © Copyright 2016 Family Physicians Inquiries Network, Inc.