HelpDesk AnswersAre computer-based interventions effective for decreasing symptoms in adolescents with major depression?Pence, Megan DO1; Rowland, Kate MD, MS2 Author Information 1Beacon Health System South Bend, IN 2Advocate Illinois Masonic FMR Chicago, IL Evidence-Based Practice 18(3):p E2-E3, March 2015. | DOI: 10.1097/01.EBP.0000540927.10345.9c Buy Metrics Abstract Evidence-Based Answer One computer-based intervention (SPARX) is at least as effective as usual care for decreasing depressive symptoms in adolescents. Another intervention (MoodGYM) has limited efficacy for adolescent boys, but may be effective for teenage girls (SOR: B, individual nonrandomized controlled trials). © Copyright 2015 Family Physicians Inquiries Network, Inc.