1Department of Otolaryngology, MacKay Memorial Hospital, Taipei, Taiwan
2Department of Audiology and Speech-Language Pathology, Mackay Medical College, New Taipei City, Taiwan
3Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan
4Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan
5Department of Otolaryngology, National Cheng Kung University Hospital, Tainan, Taiwan
6Institute of Clinical Medicine, National Cheng Kung University College of Medicine, Tainan, Taiwan
7Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan
8Department of Otorhinolaryngology-Head and Neck Surgery, China Medical University Hospital, Taichung, Taiwan
9Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
10Department of Otolaryngology-Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan
11School of Medicine, Tzu Chi University, Hualien, Taiwan
12Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan
13Department of Otolaryngology-Head and Neck Surgery, Taipei Veteran General Hospital, Taipei, Taiwan
14Institute of Molecular Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
15Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan
16Department of Medical Research, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.
Received February 27, 2021; accepted October 9, 2021; published online ahead of print December 29, 2021
P.-Y. C. and C.-C. W. conceptualized the study, ascertained clinical data, analyzed data, and wrote the article; C.-Y. T., Y.-L. L., and M.-Y. L. performed genetic examinations and analyses; J.-L. W., C.-M. W., K.-C. C., C.-F. H., H.-P. W., Y.-F. C. and T.-H. Y. collected clinical data; P.-L.C. supervised the genetic examinations and analyses; H.-C. L., T.-C.L. and C.-J.H. supervised the whole study and provided critical revision.
This study was supported by National Health Research Institute Grant (NHRI-EX110-10914PI, to C-C. W.), the Ministry of Science and Technology of Taiwan (MOST 107-2314-B-002-137-MY3, to C-C. W.), and Chang Gung Memorial Hospital (CMRPG3H0051~3, to C.-M.W.).
The authors have no conflicts of interest relevant to this article to disclose.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and text of this article on the journal’s Web site (www.ear-hearing.com).
Address for correspondence: Chen-Chi Wu, Department of Otolaryngology, National Taiwan University Hospital, 7, Chung-Shan South Rd, Taipei, Taiwan. E-mail:[email protected]
