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Mass Spectrometry for Research and Application in Therapeutic Drug Monitoring or Clinical and Forensic Toxicology

Maurer, Hans H., PhD

doi: 10.1097/FTD.0000000000000525
Review Article

Abstract: This article reviews current applications of various hyphenated low- and high-resolution mass spectrometry techniques in the field of therapeutic drug monitoring and clinical/forensic toxicology in both research and practice. They cover gas chromatography, liquid chromatography, matrix-assisted laser desorption ionization, or paper spray ionization coupled to quadrupole, ion trap, time-of-flight, or Orbitrap mass analyzers.

Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Saarland, Germany.

Correspondence: Hans H. Maurer, PhD, Department of Experimental and Clinical Toxicology, Saarland University, D-66421 Homburg, Saarland, Germany (e-mail:

The author declares no conflict of interest.

Received March 15, 2018

Accepted April 03, 2018

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