A 14-year-old female with suspected narcotic overdose had CYP2D6 genotyping performed to verify opiate intoxication. The role of pharmacogenetics in pain management and individualization of opiate pharmacotherapy is discussed.
*Division of Translational Therapeutics, Department of Paediatrics, Faculty of Medicine, University of British Columbia
†Pharmaceutical Outcomes Programme, BC Children's Hospital
‡Canadian Pharmacogenomics Network for Drug Safety
§Child and Family Research Institute
¶Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada.
The authors declare no conflict of interest.
Correspondence: Dr. Bruce C. Carleton, PharmD, Child and Family Research Institute, 950 West 28th Avenue, Rm A3-207, Vancouver, BC V5Z 4H4, Canada (e-mail: firstname.lastname@example.org).
Received November 1, 2011
Accepted January 7, 2012