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Nonsurgical Treatments for Infraorbital Rejuvenation

A Review

Lipp, Michael, DO*; Weiss, Eduardo, MD†,‡

doi: 10.1097/DSS.0000000000001897
Review Article

BACKGROUND Tear trough and infraorbital region changes are one of the first signs recognizable aging. This is a common consultation for cosmetic dermatologists and there are many treatment options available.

OBJECTIVE This article provides a review of the anatomy and changes that occur in the infraorbital region as we age. We also suggest the use of the osseous, color, underlying anatomy, laxity, adipose, rhytides (OCULAR) mnemonic to evaluate these changes and review the literature for treatments options.

MATERIALS AND METHODS A literature search was performed through PubMed, using search terms “Tear trough,” “Infra-orbital,” “Dark-circles,” “Lower-Eyelid,” and “Midface.”

RESULTS Fillers, lasers, radiofrequency devices, chemical peels, various topicals, and botulinum toxin are available non-surgical treatment options discussed in the literature found to significantly improve and rejuvenate the infraorbital region.

CONCLUSION A complete understanding of the anatomy and changes that occur with aging are of most importance when assessing the infraorbital region. Organizing these changes into the OCULAR mnemonic is one way to assess the infraorbital region and achieve optimal rejuvenation.

*Department of Dermatology, LECOMT/Larkin Community Hospital, Palm Springs Campus, Hialeah, Florida;

Hollywood Dermatology and Cosmetic Surgery Specialists, Hollywood, Florida;

University of Miami Miller School of Medicine, Miami, Florida

Address correspondence and reprint requests to: Eduardo Weiss, MD, Hollywood Dermatology and Cosmetic Surgery Specialists, 3850 Hollywood Boulevard, Suite 403, Hollywood, FL 33021, or e-mail:

The authors have indicated no significant interest with commercial supporters.

© 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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