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A 1064-nm Neodymium-doped Yttrium Aluminum Garnet Picosecond Laser for the Treatment of Hyperpigmented Scars

Koren, Amir MD*,†; Niv, Roni MD; Cohen, Sarit MD§; Artzi, Ofir MD*,†,‡

doi: 10.1097/DSS.0000000000001917
Original Article

BACKGROUND Pigmentation is one of the few major characteristics according to which scars are evaluated. Data on the treatment of the hyperpigmented component of scars are sparse.

OBJECTIVE The authors aimed at evaluating the efficacy of the fractional 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser in the treatment of the hyperpigmented component of scars.

METHODS Sixteen patients with hyperpigmented scars underwent 3 to 8 treatment sessions at 3- to 6-week intervals with the 1,064-nm Nd:YAG picosecond laser (PicoWay, Candela, Resolve handpiece). The treatment response was evaluated by 2 noninvolved dermatologists on a global assessment scale (GAS) of 1 to 4. A Mexameter quantitatively evaluated the melanin content of the scar before and after laser treatments.

RESULTS The average GAS score of the 2 noninvolved dermatologists was 3.31 ± 0.57. The patients assessed their level of tolerance as good or excellent and their satisfaction level as moderate or high. The Mexameter showed that the melanin index decreased considerably (by 39.11 ± 11.58%) in all patients after treatment.

CONCLUSION The fractionated nonablative picosecond Nd:YAG laser was effective for the treatment of the hyperpigmented component of scars.

*Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;

Epilogic Laser Center, Jerusalem, Israel;

§Department of Plastic and Reconstructive Surgery, Assaf Harofeh Medical Center, Zeriffin, Israel

Address correspondence and reprint requests to: Ofir Artzi, MD, Department of Dermatology, Tel Aviv Medical Center, 6 Weizman Street, Tel Aviv 6423906, Israel, or e-mail:

The authors have indicated no significant interest with commercial supporters.

O. Artzi initiated the study and served as the principal investigator; A. Koren analyzed the data and wrote the manuscript. R. Niv and O. Artzi performed the treatments.

© 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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