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Sustained Benefit After Treatment of Acne Vulgaris Using Only a Novel Combination of Long-Pulsed and Q-Switched 1064-nm Nd

YAG Lasers

Bakus, Abnoeal D., PhD*; Yaghmai, Dina, MD*; Massa, Mary C., MD*,†; Garden, Benjamin C., MD*,‡; Garden, Jerome M., MD*,§

doi: 10.1097/DSS.0000000000001565
Original Article

BACKGROUND Acne vulgaris remains a challenging disease to treat in many patients. Traditional therapies may have limited successes with potential side effects. Laser and light energy devices may offer a desirable alternative.

OBJECTIVE To evaluate the effectiveness and safety in using a combination laser approach with both long-pulsed (LP) and Q-switched (QS) Nd:YAG lasers in the treatment of active acne.

METHODS Twenty patients with moderate to severe inflammatory acne were treated with LP YAG laser followed immediately with QS YAG laser. Patients received at least 8 treatments. Follow-up evaluation occurred at a minimum of 12 months. Pre- and post-treatment photographs were graded by blinded physicians. All topical acne medications and oral antibiotics were discontinued throughout the therapy and follow-up period.

RESULTS There was a 81% reduction in acne lesions, with 60% of patients having 90% or greater reduction. Overall appearance was graded at 84% improvement at follow-up. Follow-up occurred at a mean of 22.7 months after completion of therapy. Aside from transient erythema, there were no other adverse effects.

CONCLUSION Active acne can be treated successfully with a combination of LP and QS YAG lasers with patients remaining off acne medications throughout laser therapy and the follow-up period.

*Physicians Laser and Dermatology Institute, Chicago, Illinois;

Department of Dermatology, Rush University Medical School, Chicago, Illinois;

Department of Dermatology, University of Illinois at Chicago, Chicago, Illinois;

§Department of Dermatology and Biomedical Engineering, Northwestern University, Chicago, Illinois

Address correspondence and reprint requests to: Jerome M. Garden, MD, Physicians Laser and Dermatology Institute, 150 E. Huron, Suite 1050, Chicago, IL 60645, or e-mail:

The authors have indicated no significant interest with commercial supporters.

© 2018 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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