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The Effects of Postoperative Intralesional Corticosteroids in the Prevention of Recurrent Earlobe Keloids

A Multispecialty Retrospective Review

Gold, Daniel A., BS*; Sheinin, Renee, MD*; Jacobsen, Gordon, MS; Jones, Lamont R., MD, MBA; Ozog, David M., MD*

doi: 10.1097/DSS.0000000000001474
Original Article

BACKGROUND Effective treatment of keloids is challenging because the recurrence rate after surgical excision is high. Data on the best treatment practices are lacking.

OBJECTIVE To investigate the recurrence rate after surgical excision of earlobe keloids based on a postoperative intralesional corticosteroid injection protocol.

MATERIALS AND METHODS Retrospective chart review was performed from January 1, 2005, to March 31, 2016, of patients who had excision of ear keloids within the departments of dermatology, otorhinolaryngology, and plastic surgery. The number of postoperative injections was recorded, recurrence was reported by the patient, and the efficacy of an injection protocol was evaluated.

RESULTS There were 277 charts reviewed. Appropriate data were available for 184 patients. A statistically significant difference was found with recurrence associated with a lower number of injections (p < .001). Keloids were more likely to recur if they were not treated with a planned serial injection protocol (p < .001) or if they were treated outside the department of dermatology (p < .001).

CONCLUSION Intralesional corticosteroid injection after surgical excision of earlobe keloids statistically minimizes the risk of recurrence.

*Department of Dermatology, Henry Ford Hospital, Detroit, Michigan;

Public Health Services, Henry Ford Hospital, Detroit, Michigan;

Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan

Address correspondence and reprint requests to: David M. Ozog, MD, Department of Dermatology, Henry Ford Medical Center–New Center One, 3031 West Grand Boulevard, Street 800, Detroit, MI 48202, or e-mail:

The authors have indicated no significant interest with commercial supporters.

© 2018 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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