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Safety and Efficacy of a Noninvasive 1,060-nm Diode Laser for Fat Reduction of the Flanks

Katz, Bruce, MD*; Doherty, Sean, MD

doi: 10.1097/DSS.0000000000001298
Original Article

BACKGROUND Preliminary reports indicate a hyperthermic diode laser treatment could be a safe and effective method for noninvasive fat reduction using the 1,060-nm wavelength. This wavelength penetrates the skin to heat subcutaneous adipocytes causing cellular disruption, leaving extracellular lipids, and cellular debris to be evacuated naturally by the body.

OBJECTIVE To evaluate the safety and effectiveness of this modality for noninvasive fat reduction of the flanks.

MATERIALS AND METHODS Forty-nine subjects received single laser treatment to 1 flank. Ultrasound images were taken at baseline, follow-up at 6 and 12 weeks after treatment. High-resolution photographs were taken at baseline and 12 weeks after treatment and then evaluated by independent reviewers. Adverse events recorded at all visits. Subjects completed a satisfaction questionnaire at the conclusion of the trial.

RESULTS Ultrasound images showed statistically significant (p < .001) average fat reduction of 2.6 ± 1.1 mm. Reviewers correctly ordered photographs 90.3% of the time. Ninety-six percentage of subjects rated that they were satisfied. Noted side effects were transient mild to moderate tenderness which subsided within 1 to 3 weeks; no serious adverse events were reported.

CONCLUSION The hyperthermic 1,060-nm diode laser treatment used in this study was safe and effective for noninvasive fat reduction of the flank.

*Juva Skin & Laser Center, Icahn School of Medicine at Mount Sinai, New York, New York;

Emerson Hospital, Concord, Massachusetts

Address correspondence and reprint requests to: Bruce Katz, MD, Juva Skin & Laser Center, Icahn School of Medicine at Mount Sinai, 60 East 56 Street, New York, NY 10022, or e-mail:

Funding for this study was provided by Cynosure Lasers.

The authors have indicated no significant interest with commercial supporters.

Study performed at Juva Skin & Laser Center, New York, NY and Emerson Hospital, Concord, MA.

© 2018 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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