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Combination Therapy in Midfacial Rejuvenation

Humphrey, Shannon MD, FRCPC, FAAD; Beleznay, Katie MD, FRCPC, FAAD; Fitzgerald, Rebecca MD, FAAD, FASDS

doi: 10.1097/DSS.0000000000000747
Original Article

BACKGROUND Facial aging in the midface reflects cumulative results of multiple intrinsic and extrinsic factors over time. Midfacial rejuvenation procedures can make a positive impact on facial attractiveness and patient satisfaction.

OBJECTIVE To review evidence and clinical experience using combination treatments for midfacial rejuvenation to achieve optimal outcomes.

MATERIALS AND METHODS This article provides a review of published scientific evidence supporting the use of combination therapy in midfacial rejuvenation. In addition, the authors share their cumulative clinical experience and best practices for combination treatments in the midface.

RESULTS Clinical experience and evidence shows that combining multiple aesthetic therapies targeting multiple aspects of the aging process provides optimal results, with greater overall efficacy and a higher level of patient satisfaction.

*Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada;

Department Medicine, University of California, Los Angeles (UCLA), Los Angeles, California

Address correspondence and reprint requests to: Shannon Humphrey, MD, FRCPC, FAAD, 820-943 West Broadway, Vancouver, British Columbia, Canada V5Z 4E1, or e-mail:

S. Humphrey is an investigator, speaker and/or consultant for Allergan, Evolus, Galderma, L'Oreal, Merz, Revance, Valeant. K. Beleznay is an investigator, speaker and/or consultant for Allergan, Evolus, Galderma, Revance, Valeant. The remaining author has indicated no significant interest with commercial supporters in regards to this work.

© 2016 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
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