Secondary Logo

Institutional members access full text with Ovid®

Share this article on:

Treatment of Skin Laxity Using Multisource, Phase-Controlled Radiofrequency in Asians: Visualized 3-Dimensional Skin Tightening Results and Increase in Elastin Density Shown Through Histologic Investigation

Tanaka, Yohei MD, PhD*,†,‡; Tsunemi, Yuichiro MD, PhD; Kawashima, Makoto MD, PhD; Tatewaki, Naoto PhD; Nishida, Hiroshi PhD

doi: 10.1111/dsu.0000000000000047
Original Article

BACKGROUND A new multisource phase-controlled radiofrequency (MPCRF) device is widely used for skin tightening and rejuvenation in Asia.

OBJECTIVE To evaluate the efficacy of MPCRF objectively and histologically.

METHODS An MPCRF device with real-time impedance control was evaluated. Ten Japanese patients were treated one side of the face, and the untreated side served as a control. Three-dimensional (3-D) imaging was performed to evaluate the posttreatment volume change. An independent observer assessed the 3-D images. Histologic evaluations of elastin were performed by Victoria Blue staining in 5 Japanese patients.

RESULTS Objective assessments evaluated by a 3-D color schematic representation showed improvement in skin laxity after the final treatment in all patients. The treated side improved markedly compared with the untreated side; however, even the untreated side slightly improved. The elastin density was significantly increased compared with controls in all 5 Japanese patients (p = .0013). Induced elastin appeared to be relatively thin elastic fibers without irregular elastic fibers, such as solar elastosis. Side effects were not observed, and the patients reported feeling comfortable throughout the study.

CONCLUSION Multisource phase-controlled radiofrequency treatments provide stimulation of elastin and skin-tightening results safely and effectively, and thus are beneficial for improving skin laxity and rhytides.

*Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, Matsumoto, Nagano, Japan;

Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan;

Department of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan

Address correspondence and reprint requests to: Yohei Tanaka, MD, PhD, Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, M-1 Bld 1F, 3-4-3, Ote, Matsumoto, Nagano 390-0874, Japan, or e-mail:

The authors have indicated no significant interest with commercial supporters.

© 2014 by the American Society for Dermatologic Surgery, Inc. Published by Lippincott Williams & Wilkins
You currently do not have access to this article

To access this article:

Note: If your society membership provides full-access, you may need to login on your society website