ORIGINAL ARTICLES: PDF OnlyBotulinum A Neurotoxin for Axillary Hyperhidrosis No Sweat BotoxGLOGAU, RICHARD G. MD1Author Information 1 Department of Dermatology, University of California, San Francisco, California. Address correspondence and reprint requests to: Richard G. Glogau, MD, 350 Parnassus Avenue, Suite 400, San Francisco, CA 94117-3685. Dermatologic Surgery: August 1998 - Volume 24 - Issue 8 - p 817-819 doi: 10.1111/j.1524-4725.1998.tb04257.x Buy Metrics Abstract background. Axillary hyperhidrosis causes considerable emotional stress and is associated with extraordinary costs and limitations in clothing. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae. Botulinum A neurotoxin (Botox) has been shown to decrease sweating in normal skin and in palmar hyperhidrosis. objective. The current study was undertaken to demonstrate the utility of using Botox in the treatment of axillary hyperhidrosis. methods. Twelve patient with axillary hyperhidrosis underwent intradermal injection with 50 units of Botox in the axillary skin bilaterally. results. All patients enjoyed relatively complete anhidrosis of the axillary skin in periods ranging from 4 to 7 months. Repeat injections produced similar results. conclusion. Botulinum A neurotoxin (Botox) is an elegant and simple treatment for axillary hyperhidrosis. © 1998 by the American Society for Dermatologic Surgery, Inc.