ARTICLE: PDF OnlyVariations and Comparisons in Medium-Depth Chemical PeelingBRODY, HAROLD J. M.D.1 Author Information 1 Harold J. Brody, M.D., is Clinical Assistant Professor of Dermatology, Emory University School of Medicine, Atlanta, Georgia. Address reprint requests to Harold J. Brody, M.D., 478 Peachtree St., N.E., Suite 711-A, Atlanta, GA 30308. The Journal of Dermatologic Surgery and Oncology 15(9):p 953-963, September 1989. | DOI: 10.1111/j.1524-4725.1989.tb03182.x Buy Metrics Abstract Two effective methods in chemical peeling, solid carbon dioxide plus trichloroacetic acid and Jessner's solution plus trichloroacetic acid, were compared clinically with photographs and histologically with serial biopsies. Carbon dioxide produced a deeper wound than Jessner's solution, and CO2+ TCA was slightly deeper than Jessner's + TCA but was probably not significantly deeper from a clinical standpoint except in correcting scarring. Triple consecutive applications of TCA can substantially increase wound depth with both combination peels. © Lippincott-Raven Publishers.